Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 20/20 | 0.63 |
| ▸ | ADRB1 | P08588 | 12/20 | 0.62 |
| ▸ | ADRB3 | P13945 | 6/20 | 0.60 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5280133 | 1.00 | ADRB2 (0.63) | ADRB2ADRB1ADRB3ADRA1D | |
| Acetic Acid SCHEMBL5292144 | 0.96 | ADRB2 (0.64) | ADRB2ADRB1ADRB3ADRA1D | |
| SCHEMBL6164334 | 0.92 | ADRB2 (0.70) | ADRB2ADRB1ADRB3ADRA1D | |
| SCHEMBL5278022 | 0.92 | ADRB2 (0.70) | ADRB2ADRB1ADRB3ADRA1D | |
| SCHEMBL5430614 | 0.90 | ADRB2 (0.74) | ADRB2ADRB1ADRB3ADRA1D | |
| SCHEMBL5430606 | 0.90 | ADRB2 (0.74) | ADRB2ADRB1ADRB3ADRA1D | |
| SCHEMBL5284339 | 0.90 | ADRB2 (0.63) | ADRB2ADRB1ADRB3ADRA1D | |
| SCHEMBL5280034 | 0.90 | ADRB2 (0.63) | ADRB2ADRB1ADRB3ADRA1D | |
| SCHEMBL5394294 | 0.90 | ADRB2 (0.63) | ADRB2ADRB1ADRB3ADRA1D | |
| SCHEMBL5277994 | 0.90 | ADRB2 (0.63) | ADRB2ADRB1ADRB3ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1497261-A1 | PHENETHANOLAMINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2005-01-19 | — | — | EP | claimed |
| WO-2003091204-A1 | PHENETHANOLAMINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2003-11-06 | — | — | WO | claimed |
| EP-1497261-A1 | PHENETHANOLAMINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2005-01-19 | — | — | EP | disclosed |
| WO-2003091204-A1 | PHENETHANOLAMINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2003-11-06 | — | — | WO | disclosed |