SCHEMBL6151829

SCHEMBL6151829

Cc1oc(C(C)C)nc1CCOc1cccc(-c2ccccc2CC(=O)O)c1.[NaH]

nearest known ligand 0.51

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PPARG P37231 20/20 0.51
PPARA Q07869 20/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6151830 0.90 PPARG (0.44) PPARGPPARA
SCHEMBL5580833 0.87 PPARG (0.66) PPARGPPARA
SCHEMBL5580634 0.86 PPARG (0.58) PPARGPPARA
SCHEMBL5580551 0.81 PPARG (0.57) PPARGPPARA
SCHEMBL5584075 0.77 PPARG (0.59) PPARGPPARA
SCHEMBL5580706 0.77 PPARG (0.55) PPARGPPARA
SCHEMBL5580762 0.75 PPARG (0.53) PPARGPPARA
SCHEMBL5584296 0.75 PPARG (0.52) PPARGPPARA
SCHEMBL13802494 0.73 PTGER1 (0.57)
SCHEMBL4391054 0.72 PPARG (0.75) PPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1604971-A1 CINNAMYL ALCOHOL DERIVATIVE COMPOUNDS AND DRUGS CONTAINING THE COMPOUNDS AS THE ACTIVE INGREDIENT ONO PHARMACEUTICAL CO., LTD. (JP) 2005-12-14 EP disclosed