Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 3/20 | 0.57 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.57 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.57 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.57 |
| ▸ | RXRA | P19793 | 1/20 | 0.55 |
| ▸ | RXRB | P28702 | 1/20 | 0.55 |
| ▸ | CFD | P00746 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.50 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.48 |
| ▸ | FABP4 | P15090 | 4/20 | 0.46 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.46 |
| ▸ | FABP3 | P05413 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ICMT | O60725 | 2/20 | 0.46 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5698013 | 0.80 | RXRA (0.55) | RXRARXRBPTGS2FABP4FABP5 | |
| SCHEMBL17796988 | 0.80 | RXRA (0.61) | RXRARXRBPTGS2FFAR1LMNA | |
| SCHEMBL4089863 | 0.79 | PTGER4 (0.59) | PTGER1PTGER4PTGER3PTGER2CFD | |
| SCHEMBL4214472 | 0.78 | RXRA (0.62) | RXRARXRBCFDENPP2FFAR1 | |
| SCHEMBL9890647 | 0.78 | PTGER1 (0.57) | PTGER1PTGER4PTGER3PTGER2PTGS2 | |
| SCHEMBL4212932 | 0.77 | RXRA (0.69) | PTGER2RXRARXRBFFAR1LMNA | |
| SCHEMBL17797039 | 0.77 | ALDH1A1 (0.60) | RXRARXRBPTGS2LMNAMAPK1 | |
| Ethane SCHEMBL28588588 | 0.77 | PTGS1 (0.57) | PTGER1PTGER4PTGER3PTGER2PTGS2 | |
| SCHEMBL538512 | 0.77 | KMT2A (0.60) | PTGER1PTGER4PTGER3PTGER2PTGS2 | |
| SCHEMBL11017769 | 0.76 | RXRA (0.51) | RXRARXRBPTGS2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090155903-A1 | PHARMACEUTICAL COMPOSITION AND METHOD | MYRIAD GENETICS, INCORPORATED (US) | 2009-06-18 | — | — | US | disclosed |
| US-20090155903-A1 | PHARMACEUTICAL COMPOSITION AND METHOD | MYRIAD GENETICS, INCORPORATED (US) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090155903-A1 | PHARMACEUTICAL COMPOSITION AND METHOD | APP, PSEN2, PSEN1 | PTGER1 1195/4885PTGER4 1561/4885PTGER3 1143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.