Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | RXRG | P48443 | 1/20 | 0.32 |
| ▸ | IKBKB | O14920 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6425424 | 1.00 | ALDH1A1 (0.41) | ALDH1A1GAATSHRCYP1A2CYP3A4 | |
| SCHEMBL6428042 | 0.90 | ALDH1A1 (0.42) | ALDH1A1CYP1A2CYP3A4CYP2D6MAPT | |
| SCHEMBL6428039 | 0.90 | ALDH1A1 (0.42) | ALDH1A1CYP1A2CYP3A4CYP2D6MAPT | |
| SCHEMBL6152251 | 0.84 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL6152240 | 0.84 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL6426491 | 0.82 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL6151821 | 0.82 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL6152062 | 0.80 | MAPT (0.43) | ALDH1A1TSHRCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9709898 | 0.76 | IKBKB (0.49) | ALDH1A1GAACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3255428 | 0.74 | NPC1 (0.44) | ALDH1A1GAATSHRCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6930208-B2 | 3-Keto- or 3- oxime-ether-substituted benzoylcyclohexanediones | BAYER CROPSCIENCE GMBH (DE) | 2005-08-16 | — | — | US | disclosed |
| EP-1497251-A1 | 3-KETO OR 3-OXIMOETHER SUBSTITUTED BENZOYLCYCLOHEXANEDIONES | Bayer CropScience GmbH (DE) | 2005-01-19 | — | — | EP | disclosed |
| US-20040204320-A1 | 3-Keto- or 3- oxime-ether-substituted benzoylcyclohexanediones | BAYER CROPSCIENCE GMBH (DE) | 2004-10-14 | — | — | US | disclosed |
| WO-2003084912-A1 | 3-KETO OR 3-OXIMOETHER SUBSTITUTED BENZOYLCYCLOHEXANEDIONES | BAYER CROPSCIENCE GMBH (DE) | 2003-10-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040204320-A1 | 3-Keto- or 3- oxime-ether-substituted benzoylcyclohexanediones | CBR3, CBR1, CYP2E1 | ALDH1A1 397/4885GAA 3394/4885TSHR 1287/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.