Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4A | P47712 | 19/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3931910 | 0.92 | PLA2G4A (0.81) | PLA2G4A | |
| SCHEMBL3924442 | 0.90 | PLA2G4A (0.80) | PLA2G4A | |
| SCHEMBL6151988 | 0.90 | PLA2G4A (0.85) | PLA2G4A | |
| SCHEMBL3930490 | 0.87 | PLA2G4A (0.80) | PLA2G4A | |
| SCHEMBL3654180 | 0.86 | PLA2G4A (0.82) | PLA2G4A | |
| SCHEMBL3933295 | 0.84 | PLA2G4A (0.81) | PLA2G4A | |
| SCHEMBL3930567 | 0.84 | PLA2G4A (0.81) | PLA2G4A | |
| SCHEMBL3931905 | 0.82 | PLA2G4A (1.00) | PLA2G4A | |
| SCHEMBL2807398 | 0.81 | PLA2G4A (0.88) | PLA2G4A | |
| SCHEMBL3924258 | 0.81 | PLA2G4A (0.72) | PLA2G4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1590324-A1 | NOVEL HETEROARYL-SUBSTITUTED ACETONE DERIVATIVES AS INHIBITORS OF PHOSPHOLIPASE A sb 2 /sb | MERCKLE GMBH (DE) | 2005-11-02 | — | — | EP | disclosed |
| WO-2004069797-A1 | NOVEL HETEROARYL-SUBSTITUTED ACETONE DERIVATIVES AS INHIBITORS OF PHOSPHOLIPASE A2 | MERCKLE GMBH (DE) | 2004-08-19 | — | — | WO | disclosed |