Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 6/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 13/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5279698 | 1.00 | ADRB2 (0.41) | ADRB2ADRB3ADRB1KDM4EGAA | |
| SCHEMBL5280870 | 1.00 | ADRB2 (0.41) | ADRB2ADRB3ADRB1KDM4EGAA | |
| SCHEMBL5288452 | 0.94 | ADRB3 (0.45) | ADRB2ADRB3ADRB1KDM4EGAA | |
| SCHEMBL5288433 | 0.94 | ADRB3 (0.45) | ADRB2ADRB3ADRB1KDM4EGAA | |
| SCHEMBL5394742 | 0.92 | ADRB2 (0.47) | ADRB2ADRB3ADRB1KDM4EGAA | |
| SCHEMBL5394748 | 0.92 | ADRB2 (0.47) | ADRB2ADRB3ADRB1KDM4EGAA | |
| SCHEMBL5282937 | 0.92 | ADRB2 (0.40) | ADRB2ADRB3ADRB1KDM4EGAA | |
| SCHEMBL5282944 | 0.92 | ADRB2 (0.40) | ADRB2ADRB3ADRB1KDM4EGAA | |
| SCHEMBL5373388 | 0.90 | ADRB2 (0.39) | ADRB2ADRB3ADRB1KDM4EGAA | |
| SCHEMBL5373383 | 0.90 | ADRB2 (0.39) | ADRB2ADRB3ADRB1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1497261-A1 | PHENETHANOLAMINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2005-01-19 | — | — | EP | disclosed |
| WO-2003091204-A1 | PHENETHANOLAMINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2003-11-06 | — | — | WO | disclosed |