Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 8/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL6152621 | 0.98 | KAT2B (0.54) | KAT2BMAPTHTTIDO1CA12 | |
| SCHEMBL7134896 | 0.89 | KAT2B (0.50) | KAT2BMAPTHTTIDO1CA12 | |
| SCHEMBL6152131 | 0.87 | CA12 (0.57) | KAT2BMAPTHTTIDO1CA12 | |
| Bromide SCHEMBL6152417 | 0.85 | CA12 (0.55) | KAT2BMAPTHTTIDO1CA12 | |
| SCHEMBL19029856 | 0.83 | KAT2B (0.52) | KAT2BMAPTHTTCA12CA3 | |
| SCHEMBL7559659 | 0.82 | MAPT (0.76) | KAT2BMAPTHTTIDO1CA12 | |
| SCHEMBL7134112 | 0.81 | KAT2B (0.57) | KAT2BMAPTHTTIDO1CA12 | |
| SCHEMBL4603846 | 0.79 | ALDH1A1 (0.53) | MAPTHTTALDH1A1HSD17B10TSHR | |
| SCHEMBL7996193 | 0.78 | MAPT (0.52) | KAT2BMAPTHTTIDO1CA12 | |
| SCHEMBL10453654 | 0.77 | MAPT (0.56) | KAT2BMAPTHTTALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1309540-B1 | OXIDIZING COLORANT | HENKEL KGAA (DE) | 2005-11-02 | — | — | EP | claimed |
| EP-0804436-B1 | GUANINE DERIVATIVE | WELLCOME FOUND (GB) | 2005-08-24 | — | — | EP | disclosed |
| EP-0874631-B1 | USE OF VALACICLOVIR FOR THE MANUFACTURE OF A MEDICAMENT FOR THE TREATMENT OF GENITAL HERPES BY A SINGLE DAILY APPLICATION | GLAXO GROUP LTD (GB) | 2003-11-19 | — | — | EP | disclosed |
| US-6107302-A | STORAGE STABLE VALACICLOVIR IN ANHYDROUS CRYSTALLINE FORM; VIRICIDE AGAINST HERPES VIRUS | GLAXO WELLCOME INC. (US) | 2000-08-22 | — | — | US | disclosed |
| EP-0806943-B1 | VALACICLOVIR TABLETS CONTAINING COLLOIDAL SILICON DIOXIDE | WELLCOME FOUND (GB) | 2000-03-15 | — | — | EP | disclosed |
| US-4689374-A | Water soluble polyamidoaminepolyamine having weight average molecular weight of at least 5×105 | W. R. GRACE & CO. (US) | 1987-08-25 | — | — | US | disclosed |