Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6153060 | 0.91 | BDKRB1 (0.34) | BDKRB1 | |
| SCHEMBL6152354 | 0.86 | CCR3 (0.33) | BDKRB1 | |
| SCHEMBL6153058 | 0.86 | CCR3 (0.33) | BDKRB1 | |
| SCHEMBL6152545 | 0.85 | CCR3 (0.32) | BDKRB1 | |
| SCHEMBL6153099 | 0.85 | CCR3 (0.33) | BDKRB1 | |
| SCHEMBL6152996 | 0.84 | POLB (0.34) | — | |
| SCHEMBL6154565 | 0.83 | CCR3 (0.34) | — | |
| SCHEMBL6152752 | 0.83 | MEN1 (0.36) | — | |
| SCHEMBL6152925 | 0.82 | L3MBTL1 (0.31) | — | |
| SCHEMBL7248590 | 0.82 | MEN1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1307449-B1 | 1,4-DIHYDROPYRIDINES AS BRADYKININ ANTAGONISTS | PFIZER PHARMA (JP) | 2005-12-07 | — | — | EP | disclosed |
| EP-1307449-A1 | 1,4-DIHYDROPYRIDINES AS BRADYKININ ANTAGONISTS | PFIZER PHARMACEUTICALS INC. (JP) | 2003-05-07 | — | — | EP | disclosed |
| WO-2002012235-A1 | 1,4-DIHYDROPYRIDINES AS BRADYKININ ANTAGONISTS | PFIZER PHARMACEUTICALS INC. (JP) | 2002-02-14 | — | — | WO | disclosed |