Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.53 |
| ▸ | PIM1 | P11309 | 1/20 | 0.53 |
| ▸ | IDO1 | P14902 | 1/20 | 0.53 |
| ▸ | LTK | P29376 | 1/20 | 0.53 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.53 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.53 |
| ▸ | TERT | O14746 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | APEX1 | P27695 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL6153155 | 0.98 | CHEK1 (0.51) | CHEK1PIM1IDO1LTKLIMK1 | |
| SCHEMBL29477145 | 0.83 | MAPT (0.64) | CHEK1PIM1IDO1LTKLIMK1 | |
| SCHEMBL18066528 | 0.83 | MAPT (0.64) | CHEK1PIM1IDO1LTKLIMK1 | |
| SCHEMBL2781417 | 0.79 | CHEK1 (0.63) | CHEK1PIM1IDO1LTKLIMK1 | |
| SCHEMBL10798671 | 0.78 | CHEK1 (0.54) | CHEK1PIM1IDO1LTKLIMK1 | |
| SCHEMBL11749512 | 0.78 | CHEK1 (0.54) | CHEK1PIM1IDO1LTKLIMK1 | |
| SCHEMBL9491481 | 0.77 | MAPT (0.49) | CHEK1PIM1IDO1LTKLIMK1 | |
| SCHEMBL5605466 | 0.76 | TERT (0.72) | CHEK1PIM1IDO1LTKLIMK1 | |
| SCHEMBL9771628 | 0.76 | KAT2B (0.49) | CHEK1PIM1IDO1LTKLIMK1 | |
| Hydrochloric Acid SCHEMBL9771678 | 0.75 | KAT2B (0.51) | CHEK1PIM1IDO1LTKLIMK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1309540-B1 | OXIDIZING COLORANT | HENKEL KGAA (DE) | 2005-11-02 | — | — | EP | claimed |
| EP-1309540-A1 | OXIDIZING COLORANT | Henkel Kommanditgesellschaft auf Aktien (DE) | 2003-05-14 | — | — | EP | claimed |
| WO-2002010118-A1 | OXIDIZING COLORANT | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2002-02-07 | — | — | WO | claimed |
| EP-1309540-B1 | OXIDIZING COLORANT | HENKEL KGAA (DE) | 2005-11-02 | — | — | EP | disclosed |
| EP-1551832-A1 | 8-AZABICYCLO[3.2.1]OCTANE ETHER DERIVATIVES AND THEIR USE AS NEUROKININ RECEPTOR ANTAGONISTS | MERCK SHARP & DOHME LTD. (GB) | 2005-07-13 | — | — | EP | disclosed |
| WO-2004031185-A1 | 8-AZABICYCLO[3.2.1]OCTANE ETHER DERIVATIVES AND THEIR USE AS NEUROKININ RECEPTOR ANTAGONISTS | MERCK SHARP & DOHME LIMITED (GB) | 2004-04-15 | — | — | WO | disclosed |
| EP-1309540-A1 | OXIDIZING COLORANT | Henkel Kommanditgesellschaft auf Aktien (DE) | 2003-05-14 | — | — | EP | disclosed |
| WO-2002010118-A1 | OXIDIZING COLORANT | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2002-02-07 | — | — | WO | disclosed |