Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 12/20 | 0.65 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6152253 | 0.89 | F10 (0.65) | F10ATMMAPTTHRBLMNA | |
| Hydrochloric Acid SCHEMBL6194130 | 0.88 | F10 (0.55) | F10ATM | |
| SCHEMBL6152664 | 0.81 | F10 (0.65) | F10ATMMAPTTHRBLMNA | |
| SCHEMBL5733762 | 0.81 | F10 (0.72) | F10ATMSMN1; SMN2LMNA | |
| SCHEMBL6306256 | 0.81 | F10 (0.67) | F10ATMSMN1; SMN2 | |
| SCHEMBL6152905 | 0.81 | F10 (0.55) | F10ATMMAPTSMN1; SMN2THRB | |
| SCHEMBL6386353 | 0.80 | F10 (0.66) | F10ATMMAPTSMN1; SMN2THRB | |
| SCHEMBL6306689 | 0.80 | F10 (0.63) | F10ATMMAPTSMN1; SMN2THRB | |
| SCHEMBL6151827 | 0.80 | F10 (0.63) | F10ATMMAPTSMN1; SMN2THRB | |
| SCHEMBL6299380 | 0.80 | F10 (0.66) | F10ATMMAPTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1082303-B1 | HETEROCYCLIC DERIVATIVES WHICH INHIBIT FACTOR XA | ASTRAZENECA AB (SE) | 2005-01-26 | — | — | EP | disclosed |
| US-6395731-B1 | ANTICOAGULANTS | ASTRAZENECA AB (SE) | 2002-05-28 | — | — | US | disclosed |
| EP-1082303-A1 | HETEROCYCLIC DERIVATIVES WHICH INHIBIT FACTOR XA | AstraZeneca AB (SE) | 2001-03-14 | — | — | EP | disclosed |
| WO-1999057099-A1 | HETEROCYCLIC DERIVATIVES WHICH INHIBIT FACTOR XA | ASTRAZENECA AB (SE) | 1999-11-11 | — | — | WO | disclosed |