Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 14/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6729226 | 0.85 | F10 (0.59) | F10ATMSMN1; SMN2 | |
| SCHEMBL6152729 | 0.84 | F10 (0.47) | F10ATMSMN1; SMN2GAALMNA | |
| Hydrochloric Acid SCHEMBL6198569 | 0.82 | ATM (0.55) | F10ATMSMN1; SMN2GAALMNA | |
| SCHEMBL6195355 | 0.82 | ATM (0.61) | F10ATMSMN1; SMN2GAALMNA | |
| Hydrochloric Acid SCHEMBL6726014 | 0.82 | ATM (0.52) | F10ATMSMN1; SMN2GAALMNA | |
| Hydrochloric Acid SCHEMBL6198123 | 0.81 | ATM (0.60) | F10ATMSMN1; SMN2GAALMNA | |
| SCHEMBL5193868 | 0.80 | ATM (0.71) | F10ATMSMN1; SMN2GAALMNA | |
| Hydrochloric Acid SCHEMBL5735796 | 0.80 | F10 (0.60) | F10ATMF2 | |
| SCHEMBL5734070 | 0.80 | SMN1; SMN2 (0.66) | F10ATMSMN1; SMN2LMNAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL6729224 | 0.80 | F10 (0.53) | F10ATMGAALMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1082303-B1 | HETEROCYCLIC DERIVATIVES WHICH INHIBIT FACTOR XA | ASTRAZENECA AB (SE) | 2005-01-26 | — | — | EP | disclosed |
| US-6395731-B1 | ANTICOAGULANTS | ASTRAZENECA AB (SE) | 2002-05-28 | — | — | US | disclosed |
| EP-1082303-A1 | HETEROCYCLIC DERIVATIVES WHICH INHIBIT FACTOR XA | AstraZeneca AB (SE) | 2001-03-14 | — | — | EP | disclosed |
| WO-1999057099-A1 | HETEROCYCLIC DERIVATIVES WHICH INHIBIT FACTOR XA | ASTRAZENECA AB (SE) | 1999-11-11 | — | — | WO | disclosed |