Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 12/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6735803 | 0.85 | F10 (0.46) | F10ATMSMN1; SMN2GAAF2 | |
| SCHEMBL5734302 | 0.84 | F10 (0.54) | F10ATMGAAF2MEN1 | |
| SCHEMBL6152519 | 0.84 | F10 (0.54) | F10ATMSMN1; SMN2GAALMNA | |
| SCHEMBL6730989 | 0.81 | F10 (0.46) | F10ATMSMN1; SMN2GAAF2 | |
| SCHEMBL6730621 | 0.81 | F10 (0.49) | F10ATMF2MEN1KMT2A | |
| SCHEMBL6727917 | 0.80 | F10 (0.49) | F10ATMSMN1; SMN2GAAF2 | |
| SCHEMBL6197720 | 0.80 | F10 (0.53) | F10ATMGAAF2MEN1 | |
| SCHEMBL6195472 | 0.80 | F10 (0.52) | F10ATMMEN1KMT2A | |
| SCHEMBL6196725 | 0.80 | F10 (0.54) | F10ATMF2MEN1KMT2A | |
| SCHEMBL5734092 | 0.80 | F10 (0.50) | F10ATMSMN1; SMN2F2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1082303-B1 | HETEROCYCLIC DERIVATIVES WHICH INHIBIT FACTOR XA | ASTRAZENECA AB (SE) | 2005-01-26 | — | — | EP | disclosed |
| US-6395731-B1 | ANTICOAGULANTS | ASTRAZENECA AB (SE) | 2002-05-28 | — | — | US | disclosed |
| EP-1082303-A1 | HETEROCYCLIC DERIVATIVES WHICH INHIBIT FACTOR XA | AstraZeneca AB (SE) | 2001-03-14 | — | — | EP | disclosed |
| WO-1999057099-A1 | HETEROCYCLIC DERIVATIVES WHICH INHIBIT FACTOR XA | ASTRAZENECA AB (SE) | 1999-11-11 | — | — | WO | disclosed |