Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | EYA2 | O00167 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12673457 | 0.82 | TDP1 (0.42) | TDP1EYA2APPACEBLM | |
| SCHEMBL19067310 | 0.82 | TDP1 (0.45) | TDP1EYA2APPACEBLM | |
| SCHEMBL12673700 | 0.81 | CASP2 (0.39) | — | |
| SCHEMBL6152987 | 0.81 | TDP1 (0.44) | TDP1EYA2APPACEBLM | |
| SCHEMBL20000671 | 0.79 | TDP1 (0.48) | TDP1EYA2APPACEBLM | |
| SCHEMBL21096057 | 0.79 | TDP1 (0.48) | TDP1EYA2APPACEBLM | |
| SCHEMBL12650478 | 0.78 | TDP1 (0.41) | TDP1EYA2APPACEBLM | |
| SCHEMBL9626421 | 0.77 | TDP1 (0.50) | TDP1EYA2APPACEBLM | |
| SCHEMBL9625579 | 0.75 | TDP1 (0.38) | TDP1EYA2APPACEBLM | |
| SCHEMBL18843665 | 0.75 | TDP1 (0.52) | TDP1EYA2APPACEBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0948361-B1 | MAGNETIC RESONANCE BLOOD POOL AGENTS | MALLINCKRODT INC (US) | 2005-01-26 | — | — | EP | claimed |
| EP-0948361-A4 | MAGNETIC RESONANCE BLOOD POOL AGENTS | MALLINCKRODT MEDICAL INC (US) | 2001-02-07 | — | — | EP | claimed |
| EP-0948361-A1 | MAGNETIC RESONANCE BLOOD POOL AGENTS | MALLINCKRODT MEDICAL, INC. (US) | 1999-10-13 | — | — | EP | claimed |
| US-5888476-A | ADMINISTERING A GADOLINIUM COMPLEX AS A CONTRAST AGENT FOR MAGNETIC RESONANCE IMAGING WHICH INCREASE RELAXIVITY OF WATER PROTONS SURROUNDING THE TISSUE | MALLINCKRODT MEDICAL, INC. (US) | 1999-03-30 | — | — | US | claimed |
| WO-1998020908-A1 | MAGNETIC RESONANCE BLOOD POOL AGENTS | MALLINCKRODT MEDICAL, INC. (US) | 1998-05-22 | — | — | WO | claimed |