Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 2/20 | 0.40 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 5/20 | 0.37 |
| ▸ | PPARA | Q07869 | 5/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | EDNRB | P24530 | 1/20 | 0.37 |
| ▸ | EDNRA | P25101 | 1/20 | 0.37 |
| ▸ | PRKDC | P78527 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6152442 | 0.89 | POLB (0.47) | POLBCA12CA1CA2CA9 | |
| SCHEMBL12394339 | 0.88 | PPARG (0.37) | MCL1ACMSDPOLBCA12CA1 | |
| SCHEMBL12394321 | 0.87 | PIM1 (0.43) | POLBHDAC8KDM4EALPLGAA | |
| SCHEMBL12394330 | 0.87 | POLB (0.41) | MCL1ACMSDPOLBCA12CA1 | |
| SCHEMBL12394336 | 0.87 | PPARG (0.44) | MCL1ACMSDPOLBCA12CA1 | |
| SCHEMBL12394337 | 0.86 | POLB (0.45) | POLBCA12CA1CA2CA9 | |
| SCHEMBL12394329 | 0.85 | PPARG (0.37) | MCL1ACMSDPOLBCA12CA1 | |
| SCHEMBL12394328 | 0.84 | PPARG (0.41) | MCL1ACMSDPOLBCA12CA1 | |
| SCHEMBL2757065 | 0.84 | POLB (0.41) | POLBKDM4EALPLGAACYP2C9 | |
| SCHEMBL14620065 | 0.82 | POLB (0.41) | POLBKDM4EALPLGAACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1253151-B1 | Pyrromethene metal complex and light emitting device composition and light emitting devices using the same | TORAY INDUSTRIES (JP) | 2005-01-12 | — | — | EP | disclosed |
| US-6805978-B2 | COMPLEX CONTAINING DIKETOPYRROLO(3,4-C)PYRROLE COMPOUND | TORAY INDUSTRIES, INC. (JP) | 2004-10-19 | — | — | US | disclosed |
| US-20030082406-A1 | Complex containing diketopyrrolo(3,4-c)pyrrole compound | TORAY INDUSTRIES, INC. (JP) | 2003-05-01 | — | — | US | disclosed |
| EP-1253151-A1 | Pyrromethene metal complex and light emitting device composition and light emitting devices using the same | TORAY INDUSTRIES, INC. (JP) | 2002-10-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030082406-A1 | Complex containing diketopyrrolo(3,4-c)pyrrole compound | PPOX, CPNE4, TP53RK | MCL1 4464/4885ACMSD 1060/4885POLB 2334/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.