Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.50 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.50 |
| ▸ | GABRP | O00591 | 1/20 | 0.50 |
| ▸ | GABRD | O14764 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.50 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.50 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.50 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.50 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.50 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18792668 | 0.93 | PAOX (0.54) | THRBLMNABLMKMT2ANPSR1 | |
| SCHEMBL724564 | 0.85 | GRIK1 (0.46) | THRBLMNABLMKMT2ANPSR1 | |
| SCHEMBL36269 | 0.81 | PAOX (0.44) | THRBLMNABLMKMT2ANPSR1 | |
| Chloromethane SCHEMBL203881 | 0.81 | GRIK1 (0.43) | THRBLMNABLMKMT2ANPSR1 | |
| Hydrochloric Acid SCHEMBL31621224 | 0.79 | PAOX (0.43) | THRBLMNABLMKMT2ANPSR1 | |
| SCHEMBL28136381 | 0.78 | FNTA (0.59) | THRBKMT2ATSHRHDAC11FNTA | |
| SCHEMBL9697782 | 0.78 | SLC22A6 (0.55) | THRBLMNAKMT2ATSHRHDAC11 | |
| SCHEMBL9158350 | 0.77 | GRIK1 (0.47) | THRBLMNABLMKMT2ANPSR1 | |
| SCHEMBL29746160 | 0.76 | FNTA (0.69) | THRBKMT2ATSHRHDAC11FNTA | |
| SCHEMBL4746775 | 0.76 | THRB (0.44) | THRBLMNABLMKMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1278809-B1 | SILICONE/ADHESIVE COMPLEX WHEREOF THE INTERFACE HAS A RELEASE FORCE CAPABLE OF BEING MODULATED BY ELECTRON BEAM IRRADIATION | RHODIA CHIMIE SA (FR) | 2005-11-09 | — | — | EP | claimed |
| US-5750781-A | ALLYLAMINE COMPOUNDS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-05-12 | — | — | US | disclosed |