Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 11/20 | 0.47 |
| ▸ | ITGB1 | P05556 | 11/20 | 0.47 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.42 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.41 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6402915 | 1.00 | ITGA4 (0.47) | ITGA4ITGB1ITGB7CHRM4ITGA2 | |
| SCHEMBL6402913 | 1.00 | ITGA4 (0.47) | ITGA4ITGB1ITGB7CHRM4ITGA2 | |
| SCHEMBL6159009 | 0.92 | ITGB1 (0.49) | ITGA4ITGB1ITGB7 | |
| SCHEMBL6147636 | 0.92 | ITGB1 (0.49) | ITGA4ITGB1ITGB7 | |
| SCHEMBL6150353 | 0.92 | ITGB1 (0.49) | ITGA4ITGB1ITGB7 | |
| SCHEMBL6401978 | 0.90 | ITGB1 (0.48) | ITGA4ITGB1ITGB7ITGA2 | |
| SCHEMBL6149415 | 0.90 | ITGB1 (0.48) | ITGA4ITGB1ITGB7ITGA2 | |
| SCHEMBL6401982 | 0.90 | ITGB1 (0.48) | ITGA4ITGB1ITGB7ITGA2 | |
| SCHEMBL6149727 | 0.83 | ITGA4 (0.44) | ITGA4ITGB1ITGB7ITGA2ITGB3 | |
| SCHEMBL6402116 | 0.83 | ITGA4 (0.44) | ITGA4ITGB1ITGB7ITGA2ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1495044-A1 | HETEROCYCLIC AMIDES WITH ALPHA-4 INTEGRIN ANTAGONIST ACTIVITY | J. Uriach y Compania S.A. (ES) | 2005-01-12 | — | — | EP | disclosed |
| WO-2003084984-A1 | HETEROCYCLIC AMIDES WITH ALPHA-4 INTEGRIN ANTAGONIST ACTIVITY | J. URIACH Y COMPANIA S.A. (ES) | 2003-10-16 | — | — | WO | disclosed |