⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27621453 | 0.97 | — | — | |
| SCHEMBL29277835 | 0.91 | CYP3A4 (0.32) | — | |
| SCHEMBL180314 | 0.81 | — | — | |
| Water SCHEMBL8015768 | 0.77 | — | — | |
| SCHEMBL43352 | 0.77 | — | — | |
| SCHEMBL29183868 | 0.75 | ENPP2 (0.31) | — | |
| SCHEMBL27654076 | 0.74 | — | — | |
| SCHEMBL1135190 | 0.74 | — | — | |
| SCHEMBL8672502 | 0.74 | — | — | |
| SCHEMBL27647553 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2639 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118344303-A | Benzo [ c ] [1,5] oxazacine compound and synthesis method thereof | 江苏师范大学 | 2024-07-16 | — | — | CN | claimed |
| CN-118290298-A | Benzoyl hydrazine compound and synthetic method and application thereof | 南京农业大学 | 2024-07-05 | — | — | CN | claimed |
| US-20240208902-A1 | CYCLOBUTYL AMIDE MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2024-06-27 | — | — | US | claimed |
| WO-2024118801-A1 | LINEAR HETEROARYL DIAMIDE IRE1/XBP1S ACTIVATORS | PROTEGO BIOPHARMA, INC. (US) | 2024-06-06 | — | — | WO | claimed |
| US-20240174603-A1 | MODULATORS OF PROTEIN PHOSPHATASE 2A (PP2A) AND METHODS USING SAME | RAPPTA THERAPEUTICS OY (FI) | 2024-05-30 | — | — | US | claimed |
| CN-118019736-A | Molecular gel compound designed based on cereblon protein and application thereof | 标新生物医药科技(上海)有限公司 | 2024-05-10 | — | — | CN | claimed |
| EP-3893645-B1 | SUBSTITUTED ARYLMETHYLUREAS AND HETEROARYLMETHYLUREAS, ANALOGUES THEREOF, AND METHODS USING SAME | ARBUTUS BIOPHARMA CORP (CA) | 2024-04-17 | — | — | EP | claimed |
| EP-3750894-B1 | UREA-SUBSTITUTED AROMATIC RING-LINKED DIOXAZOLINE COMPOUND, PREPARATION METHOD THEREFOR, AND USES THEREOF | BEIJING SCITECH MQ PHARMACEUTICALS LTD (CN) | 2024-04-03 | — | — | EP | claimed |
| WO-2024051766-A1 | MOLECULAR GLUE COMPOUND BASED ON CEREBLON PROTEIN DESIGN AND USE THEREOF | 标新生物医药科技(上海)有限公司 | 2024-03-14 | — | — | WO | claimed |
| US-11905244-B2 | Chemical modulators of store-operated calcium channels and their therapeutic applications | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2024-02-20 | — | — | US | claimed |
| EP-0066922-A1 | Process for preparing asymmetric ureas from urethans and amines | ANIC S.p.A. (IT) | 1982-12-15 | — | — | EP | claimed |
| US-4332805-A | FOR HUMAN AND VETERINARY MEDICINE | SANOFI (FR) | 1982-06-01 | — | — | US | claimed |
| US-4293553-A | ANTITHROMBOTIC AGENT | Ishikawa, Masayuki (JP) | 1981-10-06 | — | — | US | claimed |
| US-4272280-A | Isobenzofurandione thiosemicarbazones and use as plant growth regulators | GULF OIL CORPORATION (US) | 1981-06-09 | — | — | US | claimed |
| US-4166827-A | DENTAL PLAQUE | COOPER LABORATORIES, INC. (US) | 1979-09-04 | — | — | US | claimed |
| US-4115448-A | Carbamylguanidine antimicrobial compounds | COOPER LABORATORIES, INC. (US) | 1978-09-19 | — | — | US | claimed |
| US-4110328-A | Bis-carbamylguanidinoazaalkane antimicrobial compounds | COOPER LABORATORIES, INC. (US) | 1978-08-29 | — | — | US | claimed |
| US-4022962-A | DENTAL PLAQUE INHIBITORS | COOPER LABORATORIES, INC. (US) | 1977-05-10 | — | — | US | claimed |
| US-4002660-A | ANTIBACTERIAL AGENTS | MORTON-NORWICH PRODUCTS, INC. (US) | 1977-01-11 | — | — | US | claimed |
| US-3983116-A | Herbicidal triazines | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-09-28 | — | — | US | claimed |