Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 4/20 | 0.47 |
| ▸ | BCL2 | P10415 | 3/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 4/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | RGS12 | O14924 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12604897 | 0.84 | MAPT (0.51) | BCL2KEAP1NFE2L2CRHBPCRHR2 | |
| SCHEMBL11346047 | 0.80 | BCL2 (0.60) | TYMSBCL2MAPTTDP1KDM4E | |
| SCHEMBL11352753 | 0.79 | TYMS (0.62) | TYMSBCL2KMT2AMEN1TDP1 | |
| SCHEMBL14962978 | 0.78 | KEAP1 (0.40) | BCL2KEAP1NFE2L2CRHBPCRHR2 | |
| SCHEMBL30516566 | 0.76 | USP2 (0.65) | TYMSKEAP1NFE2L2CRHBPCRHR2 | |
| SCHEMBL29556131 | 0.76 | USP2 (0.65) | TYMSKEAP1NFE2L2CRHBPCRHR2 | |
| SCHEMBL1025154 | 0.76 | USP2 (0.65) | TYMSKEAP1NFE2L2CRHBPCRHR2 | |
| SCHEMBL6153260 | 0.75 | GFER (0.42) | GFERKMT2AMEN1MAPTCYP1A2 | |
| SCHEMBL4087242 | 0.74 | TYMS (0.51) | TYMSBCL2KEAP1NFE2L2CRHBP | |
| SCHEMBL10267341 | 0.71 | TYMS (0.70) | TYMSKEAP1NFE2L2CRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5347019-A | REACTING 4-HALONAPHTHALIC ANHYDRIDES WITH 2-AMINOTHIOPHENOLATES | CASSELLA AG (DE) | 1994-09-13 | — | — | US | claimed |
| JP-6080660-A | — | — | None | — | — | JP | disclosed |
| US-20230151219-A1 | COLORANT, MASTER BATCH CONTAINING SAME, COLORED RESIN COMPOSITION, AND MOLDED ARTICLE | ORIENT CHEMICAL INDUSTRIES CO., LTD. (JP) | 2023-05-18 | — | — | US | disclosed |
| US-20230151219-A1 | COLORANT, MASTER BATCH CONTAINING SAME, COLORED RESIN COMPOSITION, AND MOLDED ARTICLE | ORIENT CHEMICAL INDUSTRIES CO., LTD. (JP) | 2023-05-18 | — | — | US | disclosed |
| EP-4134396-A1 | COLORANT, MASTER BATCH CONTAINING SAME, COLORED RESIN COMPOSITION, AND MOLDED ARTICLE | Orient Chemical Industries Co., Ltd. (JP) | 2023-02-15 | — | — | EP | disclosed |
| WO-2020099793-A1 | NOVEL BENZOTHIOXANTHENE P-CONJUGATED MOLECULES FOR ENERGY STORAGE | UNIVERSITE D'ANGERS (FR) | 2020-05-22 | — | — | WO | disclosed |
| EP-1517316-A1 | New azo type dyes for optical data recording | CLARIANT INTERNATIONAL LTD. (CH) | 2005-03-23 | — | — | EP | disclosed |
| US-5347019-A | REACTING 4-HALONAPHTHALIC ANHYDRIDES WITH 2-AMINOTHIOPHENOLATES | CASSELLA AG (DE) | 1994-09-13 | — | — | US | disclosed |
| US-5347019-A | REACTING 4-HALONAPHTHALIC ANHYDRIDES WITH 2-AMINOTHIOPHENOLATES | CASSELLA AG (DE) | 1994-09-13 | — | — | US | disclosed |
| US-5347019-A | REACTING 4-HALONAPHTHALIC ANHYDRIDES WITH 2-AMINOTHIOPHENOLATES | CASSELLA AG (DE) | 1994-09-13 | — | — | US | disclosed |
| JP-H0680660-A | PREPARATION OF 4-(2-AMINOPHENYLTHIO)NAPHTHALIC ANHYDRIDE DERIVATIVE | CASSELLA AG | 1994-03-22 | — | — | JP | disclosed |
| EP-0570778-A1 | Process for the preparation of 4-(2-aminophenylthio)-naphthalene 1-8 dicarboxylic acid anhydride derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-24 | — | — | EP | disclosed |
| EP-0570778-A1 | Process for the preparation of 4-(2-aminophenylthio)-naphthalene 1-8 dicarboxylic acid anhydride derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-24 | — | — | EP | disclosed |
| US-4254109-A | INHIBIT LENS ALDOSE REDUCTASE | AYERST, MCKENNA & HARRISON INC. (CA) | 1981-03-03 | — | — | US | disclosed |