Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 3/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | TK2 | O00142 | 8/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | TK1 | P04183 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30903369 | 0.84 | TYMP (0.60) | TYMPMAPK1TK2HPGDTK1 | |
| SCHEMBL15110503 | 0.83 | TK2 (0.60) | TYMPMAPK1TK2HPGDTK1 | |
| SCHEMBL4118603 | 0.81 | MAPK1 (0.57) | TYMPMAPK1TK2HPGDTK1 | |
| SCHEMBL7215300 | 0.81 | MAPK1 (0.57) | TYMPMAPK1TK2HPGDTK1 | |
| SCHEMBL13402919 | 0.81 | TYMP (0.54) | TYMPMAPK1TK2HPGDTK1 | |
| SCHEMBL23453029 | 0.80 | TYMP (0.59) | TYMPMAPK1TK2HPGDTK1 | |
| SCHEMBL4261186 | 0.80 | MAPK1 (0.56) | TYMPMAPK1TK2HPGDTK1 | |
| SCHEMBL4194710 | 0.80 | MAPK1 (0.56) | TYMPMAPK1TK2HPGDTK1 | |
| SCHEMBL5017275 | 0.80 | MAPK1 (0.56) | TYMPMAPK1TK2HPGDTK1 | |
| SCHEMBL3854773 | 0.80 | TYMP (1.00) | TYMPMAPK1TK2HPGDTK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024137663-A2 | TREATMENT OF DKK2 RELATED DISEASES AND DISORDERS | EMPIRICO INC. (US) | 2024-06-27 | — | — | WO | disclosed |
| WO-2023245118-A2 | TREATMENT OF MS4A4E RELATED DISEASES AND DISORDERS | EMPIRICO INC. (US) | 2023-12-21 | — | — | WO | disclosed |
| EP-1499627-A2 | NUCLEASE RESISTANT CHIMERIC OLIGONUCLEOTIDES | ISIS Pharmaceuticals, Inc. (US) | 2005-01-26 | — | — | EP | disclosed |
| WO-2003004602-A2 | NUCLEASE RESISTANT CHIMERIC OLIGONUCLEOTIDES | ISIS PHARMACEUTICALS, INC. (US) | 2003-01-16 | — | — | WO | disclosed |