SCHEMBL3854773

SCHEMBL3854773

Cc1cn(CCOCP(=O)(O)O)c(=O)[nH]c1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TYMP P19971 4/20 1.00
TK2 O00142 8/20 0.52
MAPK1 P28482 1/20 0.46
HPGD P15428 1/20 0.44
TK1 P04183 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8720003 0.91 TYMP (0.82) TYMPTK2TK1
SCHEMBL8713764 0.81 TYMP (0.67) TYMPMAPK1HPGD
SCHEMBL6153435 0.80 TYMP (0.66) TYMPTK2MAPK1HPGDTK1
SCHEMBL16037866 0.80 TYMP (0.65) TYMPTK2MAPK1TK1
SCHEMBL19181390 0.78 TYMP (0.63) TYMPTK2HPGDTK1
SCHEMBL17583277 0.77 TYMP (0.63) TYMPTK2MAPK1HPGDTK1
SCHEMBL8780707 0.76 TYMP (0.61) TYMPTK2MAPK1HPGDTK1
SCHEMBL20586239 0.76 TYMP (0.61) TYMPTK2MAPK1TK1
SCHEMBL19929317 0.76 TYMP (0.60) TYMPTK2MAPK1HPGDTK1
SCHEMBL30903369 0.75 TYMP (0.60) TYMPTK2MAPK1HPGDTK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 446 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144896-A1 MODIFIED CPG DINUCLEOTIDES FOR RECOMBINANT VIRAL VECTOR PRODUCTION SIREN BIOTECHNOLOGY, INC. (US) 2026-05-28 US claimed
EP-4598543-A2 MODIFIED CPG DINUCLEOTIDES FOR RECOMBINANT VIRAL VECTOR PRODUCTION Siren Biotechnology, Inc. (US) 2025-08-13 EP claimed
CN-120158382-A Rhodosporidium toruloides strain with high homologous recombination efficiency and construction method and application thereof 中国科学院大连化学物理研究所 2025-06-17 CN claimed
CN-119150816-B Free text-based common sense knowledge editing method and device and electronic equipment 北京智源人工智能研究院 2025-03-07 CN claimed
CN-119150816-A Free text-based common sense knowledge editing method and device and electronic equipment 北京智源人工智能研究院 2024-12-17 CN claimed
US-20240345289-A1 OCEAN-ONTO-LAND DROUGHT (OTLD) IDENTIFICATION AND PROPAGATION MECHANISM ANALYSIS METHOD AND SYSTEM CHINA UNIVERSITY OF GEOSCIENCES (WUHAN) (CN) 2024-10-17 US claimed
CN-111581861-B Continuous damage prediction method and system for high-temperature oxidation corrosion of high-chromium steel member 华南理工大学 2024-05-28 CN claimed
WO-2024077089-A2 MODIFIED CPG DINUCLEOTIDES FOR RECOMBINANT VIRAL VECTOR PRODUCTION SIREN BIOTECHNOLOGY, INC. (US) 2024-04-11 WO claimed
US-20240084283-A1 MODIFIED DDAH POLYPEPTIDES COMPRISING A PHARMACOKINETIC ENHANCING MOIETY, IMPROVED PHARMACOLOGY AND THEIR USES UNIV INDIANA TRUSTEES (US) 2024-03-14 US claimed
CN-111632153-B Chemical gene drug co-loaded targeting nano drug delivery system and preparation method thereof 宁夏医科大学 2023-02-24 CN claimed
EP-3059645-B1 METHOD AND COMPUTER PROGRAM PRODUCT FOR CONTROLLING ANAEROBIC CODIGESTERS UNIV SANTIAGO COMPOSTELA (ES) 2022-06-01 EP claimed
US-11342522-B2 White-light QLED component, backlight module and illumination apparatus NATIONAL TSING HUA UNIVERSITY (TW) 2022-05-24 US claimed
CN-109939241-B Double-prodrug co-assembled nano-targeting drug delivery system and preparation method thereof 宁夏医科大学 2022-02-15 CN claimed
US-20260144896-A1 MODIFIED CPG DINUCLEOTIDES FOR RECOMBINANT VIRAL VECTOR PRODUCTION SIREN BIOTECHNOLOGY, INC. (US) 2026-05-28 US disclosed
US-12636376-B2 Methods and compositions for use of growth factor antibodies in combination with non-tyrosine targeting kinase inhibitors IN3BIO LTD. (BM) 2026-05-26 US disclosed
US-20260139239-A1 VARIANTS OF TEV PROTEASE AND USES THEREOF NUMAFERM GMBH (DE) 2026-05-21 US disclosed
WO-2006114065-A2 USE OF COMPOUNDS TO INHIBIT NEOPLASIA INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY A CADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) 2006-11-02 WO disclosed
WO-2005123729-A1 LEWIS ACID MEDIATED SYNTHESIS OF CYCLIC ESTERS METABASIS THERAPEUTICS, INC. (US) 2005-12-29 WO disclosed
US-20050282782-A1 Lewis acid mediated synthesis of cyclic esters CITIBANK, N.A., AS ADMINISTRATIVE AGENT 2005-12-22 US disclosed
US-20050026902-A1 Methods and compositions for the treatment or prevention of human immunodeficiency virus and related conditions using cyclooxygenase-2 selective inhibitors and antiviral agents PHARMACIA CORPORATION 2005-02-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260139239-A1 VARIANTS OF TEV PROTEASE AND USES THEREOF CTRL, MME, MMEL1 TYMP 1592/4885TK2 3979/4885MAPK1 3659/4885
US-12636376-B2 Methods and compositions for use of growth factor antibodies in combination with non-tyrosine targeting kinase inhibitors BRAF, TTK, CKS1B TYMP 1123/4885TK2 2619/4885MAPK1 824/4885
US-20240084283-A1 MODIFIED DDAH POLYPEPTIDES COMPRISING A PHARMACOKINETIC ENHANCING MOIETY, IMPROVED PHARMACOLOGY AND THEIR USES DDAH1, ADM2, NPPA TYMP 582/4885TK2 1445/4885MAPK1 3910/4885
US-20050282782-A1 Lewis acid mediated synthesis of cyclic esters PHOSPHO1, LPAR1, LPAR2 TYMP 894/4885TK2 2304/4885MAPK1 815/4885
US-20050026902-A1 Methods and compositions for the treatment or prevention of human immunodeficiency virus and related conditions using cyclooxygenase-2 selective inhibitors and antiviral agents PTGS2, PTGS1, PTGES2 TYMP 46/4885TK2 222/4885MAPK1 2372/4885
US-20260144896-A1 MODIFIED CPG DINUCLEOTIDES FOR RECOMBINANT VIRAL VECTOR PRODUCTION DNMT3L, TRMT1L, SPPL2A TYMP 399/4885TK2 2165/4885MAPK1 1237/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.