Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7437563 | 0.79 | ADORA2A (0.31) | ADORA2A | |
| SCHEMBL9083885 | 0.79 | ADORA2A (0.31) | ADORA2A | |
| SCHEMBL6272960 | 0.79 | PDE8B (0.44) | ADORA1 | |
| SCHEMBL9082502 | 0.79 | ADORA2A (0.40) | ADORA1ADORA2A | |
| SCHEMBL7437584 | 0.73 | PDE8B (0.31) | — | |
| SCHEMBL6270235 | 0.72 | CDK1 (0.47) | ADORA1ADORA2A | |
| SCHEMBL9233825 | 0.72 | CDK1 (0.47) | ADORA1ADORA2A | |
| SCHEMBL7434489 | 0.70 | PDE5A (0.34) | — | |
| SCHEMBL4883772 | 0.70 | — | — | |
| SCHEMBL5277925 | 0.69 | ADORA1 (0.35) | ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1014995-A4 | COMPOSITIONS AND METHODS FOR PREVENTING RESTENOSIS FOLLOWING REVASCULARIZATION PROCEDURES | ADERIS PHARMACEUTICALS INC (US) | 2005-02-16 | — | — | EP | disclosed |
| EP-1014995-A1 | COMPOSITIONS AND METHODS FOR PREVENTING RESTENOSIS FOLLOWING REVASCULARIZATION PROCEDURES | Discovery Therapeutics, Inc. (US) | 2000-07-05 | — | — | EP | disclosed |
| WO-1998057651-A1 | COMPOSITIONS AND METHODS FOR PREVENTING RESTENOSIS FOLLOWING REVASCULARIZATION PROCEDURES | DISCOVERY THERAPEUTICS, INC. (US) | 1998-12-23 | — | — | WO | disclosed |