Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 7/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.31 |
| ▸ | PDE8B | O95263 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7437563 | 0.85 | ADORA2A (0.31) | ADORA2A | |
| SCHEMBL9083885 | 0.85 | ADORA2A (0.31) | ADORA2A | |
| SCHEMBL7437584 | 0.79 | PDE8B (0.31) | PDE8B | |
| SCHEMBL6153485 | 0.79 | ADORA1 (0.36) | ADORA2AADORA1 | |
| SCHEMBL9233825 | 0.77 | CDK1 (0.47) | ADORA2AADORA1ADORA2B | |
| SCHEMBL6270235 | 0.77 | CDK1 (0.47) | ADORA2AADORA1ADORA2B | |
| SCHEMBL7434489 | 0.72 | PDE5A (0.34) | — | |
| SCHEMBL4879686 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL4885433 | 0.68 | — | — | |
| SCHEMBL6979264 | 0.67 | MEN1 (0.36) | ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5565566-A | N6-(ENDO(1R,2S,4S)-2-NORBORNYL)-9-METHYLADENINE OR N6-(ENDO(1S,2R,4R)-2-NORBORNYL)-9-METHYLADENINE | DISCOVERY THERAPEUTICS, INC. (US) | 1996-10-15 | — | — | US | disclosed |