Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.67 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | RRM1 | P23921 | 2/20 | 0.57 |
| ▸ | RRM2B | Q7LG56 | 2/20 | 0.57 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.57 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.54 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.54 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.54 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | AR | P10275 | 1/20 | 0.51 |
| ▸ | PTGES | O14684 | 1/20 | 0.51 |
| ▸ | VCP | P55072 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL330472 | 0.89 | KMT2A (0.61) | RAB9ANPC1RRM1RRM2BMEN1 | |
| SCHEMBL7231423 | 0.88 | RAB9A (0.80) | RAB9ANPC1RRM1RRM2BGSTO1 | |
| SCHEMBL7239776 | 0.88 | RAB9A (0.80) | RAB9ANPC1RRM1RRM2BGSTO1 | |
| SCHEMBL27582671 | 0.84 | SCD (0.60) | RAB9ANPC1RRM1RRM2BCSNK2A1 | |
| SCHEMBL27582684 | 0.84 | CSNK2A2 (0.56) | RAB9ANPC1RRM1RRM2BCSNK2A1 | |
| SCHEMBL7239525 | 0.81 | RAB9A (0.86) | RAB9ANPC1RRM1RRM2BGSTO1 | |
| SCHEMBL7239062 | 0.81 | RAB9A (1.00) | RAB9ANPC1RRM1RRM2BGSTO1 | |
| SCHEMBL7235764 | 0.78 | RAB9A (0.77) | RAB9ANPC1GSTO1CSNK2A1MEN1 | |
| SCHEMBL30581066 | 0.77 | RAB9A (0.78) | RAB9ANPC1RRM1RRM2BGSTO1 | |
| SCHEMBL5099990 | 0.77 | RAB9A (0.76) | RAB9ANPC1RRM1RRM2BGSTO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050065118-A1 | Organosulfur inhibitors of tyrosine phosphatases | METABASIS THERAPEUTICS, INC. | 2005-03-24 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050065118-A1 | Organosulfur inhibitors of tyrosine phosphatases | PTPRS, PTPRJ, PTPRCAP | RAB9A 3814/4885NPC1 4548/4885RRM1 2553/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.