SCHEMBL6153687

SCHEMBL6153687

COc1cccc(C2(CNC(=O)Nc3c(C(C)C)cc(NC(=O)O)cc3C(C)C)CCN(c3ncccc3O)CC2)c1

nearest known ligand 0.71

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SOAT1 P35610 14/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6153031 0.91 SOAT1 (0.76) SOAT1
SCHEMBL6502542 0.89 SOAT1 (0.61) SOAT1
SCHEMBL6153561 0.89 SOAT1 (0.61) SOAT1
SCHEMBL6152616 0.84 SOAT1 (0.78) SOAT1
SCHEMBL6153387 0.81 SOAT1 (0.72) SOAT1
SCHEMBL6153328 0.81 SOAT1 (0.71) SOAT1
SCHEMBL6153447 0.81 SOAT1 (0.71) SOAT1
SCHEMBL6153954 0.81 SOAT1 (0.71) SOAT1
SCHEMBL6153254 0.80 SOAT1 (0.72) SOAT1
SCHEMBL6152699 0.79 SOAT1 (0.68) SOAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1500648-A1 NOVEL PIPERIDINE DERIVATIVE SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 2005-01-26 EP disclosed