⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31561489 | 0.67 | PDPK1 (0.45) | — | |
| SCHEMBL462247 | 0.67 | PDPK1 (0.45) | — | |
| SCHEMBL6153814 | 0.65 | — | — | |
| SCHEMBL11007134 | 0.63 | — | — | |
| SCHEMBL839587 | 0.55 | — | — | |
| SCHEMBL3790626 | 0.51 | — | — | |
| SCHEMBL8628192 | 0.49 | — | — | |
| SCHEMBL626919 | 0.47 | — | — | |
| SCHEMBL3931923 | 0.45 | — | — | |
| Bromide SCHEMBL8417552 | 0.42 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1499627-A2 | NUCLEASE RESISTANT CHIMERIC OLIGONUCLEOTIDES | ISIS Pharmaceuticals, Inc. (US) | 2005-01-26 | — | — | EP | claimed |
| US-20040033973-A1 | Compounds and oligomeric compounds comprising novel nucleobases | ISIS PHARMACEUTICALS, INC. | 2004-02-19 | — | — | US | claimed |
| US-20030207804-A1 | Modified peptide nucleic acids | ISIS PHARMACEUTICALS, INC. | 2003-11-06 | — | — | US | claimed |
| US-20030175906-A1 | Nuclease resistant chimeric oligonucleotides | ISIS PHARMACEUTICALS, INC. | 2003-09-18 | — | — | US | claimed |
| US-20030158403-A1 | Nuclease resistant chimeric oligonucleotides | ISIS PHARMACEUTICALS, INC. | 2003-08-21 | — | — | US | claimed |
| WO-2003004602-A2 | NUCLEASE RESISTANT CHIMERIC OLIGONUCLEOTIDES | ISIS PHARMACEUTICALS, INC. (US) | 2003-01-16 | — | — | WO | claimed |
| WO-2002097134-A2 | MODIFIED PEPTIDE NUCLEIC ACID | ISIS PHARMACEUTICALS, INC. (US) | 2002-12-05 | — | — | WO | claimed |
| US-20040033973-A1 | Compounds and oligomeric compounds comprising novel nucleobases | ISIS PHARMACEUTICALS, INC. | 2004-02-19 | — | — | US | disclosed |
| US-20030207804-A1 | Modified peptide nucleic acids | ISIS PHARMACEUTICALS, INC. | 2003-11-06 | — | — | US | disclosed |
| WO-2002097134-A2 | MODIFIED PEPTIDE NUCLEIC ACID | ISIS PHARMACEUTICALS, INC. (US) | 2002-12-05 | — | — | WO | disclosed |
| US-5599582-A | Adhesive layer in multi-level packaging and organic material as a metal diffusion barrier | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1997-02-04 | — | — | US | disclosed |
| US-5582858-A | Adhesive layer in multi-level packaging and organic material as a metal diffusion barrier | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1996-12-10 | — | — | US | disclosed |
| US-5569739-A | Adhesive layer in multi-level packaging and organic material as a metal diffusion barrier | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1996-10-29 | — | — | US | disclosed |
| US-5326643-A | Adhesive layer in multi-level packaging and organic material as a metal diffusion barrier | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1994-07-05 | — | — | US | disclosed |
| EP-0536606-A2 | An adhesive layer in multilevel packaging and organic material as a metal diffusion barrier | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1993-04-14 | — | — | EP | disclosed |