Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12218459 | 0.88 | MAPT (0.62) | MAPTALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL10938044 | 0.84 | PTPRF (0.60) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL7338580 | 0.81 | PTPRF (0.69) | MAPTALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL6754268 | 0.80 | MAPT (0.56) | MAPTALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL25920577 | 0.80 | MAPT (0.62) | MAPTALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL30301289 | 0.80 | CYP1A2 (0.65) | MAPTALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL25920592 | 0.79 | ALDH1A1 (0.61) | MAPTALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL13623067 | 0.79 | ALDH1A1 (0.61) | MAPTALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL5605070 | 0.78 | PTPRF (0.69) | MAPTALDH1A1KDM4ETDP1MEN1 | |
| Hydrochloric Acid SCHEMBL1075280 | 0.78 | ALDH1A1 (0.60) | MAPTALDH1A1KDM4ETDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050065118-A1 | Organosulfur inhibitors of tyrosine phosphatases | METABASIS THERAPEUTICS, INC. | 2005-03-24 | — | — | US | disclosed |
| EP-1446110-A2 | ORGANOSULFUR INHIBITORS OF TYROSINE PHOSPHATASES | Structural Bioinformatics Inc. (US) | 2004-08-18 | — | — | EP | disclosed |
| WO-2003032916-A2 | ORGANOSULFUR INHIBITORS OF TYROSINE PHOSPHATASES | STRUCTURAL BIOINFORMATICS INC. (US) | 2003-04-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050065118-A1 | Organosulfur inhibitors of tyrosine phosphatases | PTPRS, PTPRJ, PTPRCAP | MAPT 3318/4885ALDH1A1 961/4885KDM4E 1133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.