Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | ALPI | P09923 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | XIAP | P98170 | 1/20 | 0.48 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | CTRB1 | P17538 | 4/20 | 0.44 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALPG | P10696 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6155033 | 0.91 | ALDH1A1 (0.53) | ALDH1A1ALPIPKMPTGS1XIAP | |
| SCHEMBL6154390 | 0.91 | ALDH1A1 (0.53) | ALDH1A1ALPIPKMPTGS1XIAP | |
| SCHEMBL6153592 | 0.91 | ALDH1A1 (0.53) | ALDH1A1ALPIPKMPTGS1XIAP | |
| Acetic Acid SCHEMBL8073472 | 0.90 | ALDH1A1 (0.51) | ALDH1A1ALPIPKMPTGS1XIAP | |
| Acetic Acid SCHEMBL8073475 | 0.90 | ALDH1A1 (0.51) | ALDH1A1ALPIPKMPTGS1XIAP | |
| SCHEMBL16349153 | 0.89 | ALDH1A1 (0.50) | ALDH1A1ALPIPKMPTGS1XIAP | |
| SCHEMBL6154154 | 0.88 | ALDH1A1 (0.46) | ALDH1A1ALPIPKMPTGS1XIAP | |
| SCHEMBL6153593 | 0.88 | ALDH1A1 (0.46) | ALDH1A1ALPIPKMPTGS1XIAP | |
| SCHEMBL6154318 | 0.88 | ALDH1A1 (0.46) | ALDH1A1ALPIPKMPTGS1XIAP | |
| SCHEMBL8722335 | 0.86 | ALDH1A1 (0.44) | ALDH1A1ALPIPKMPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0916654-B1 | SULFONIC ESTER DERIVATIVES, PROCESS FOR PREPARING THE SAME, AND USE THEREOF | KANEKA CORP (JP) | 2005-02-23 | — | — | EP | disclosed |
| US-6410773-B1 | OPTICAL ACTIVE MATERIAL; ENKEPHALINASE INHIBITORS; HYPOTENSIVE AGENTS | KANEKA CORPORATION (JP) | 2002-06-25 | — | — | US | disclosed |
| EP-0906900-B1 | A process for preparing optically active 2-hydroxy-methyl-3-phenylpropionic acid | AJINOMOTO KK (JP) | 2002-01-23 | — | — | EP | disclosed |
| US-6121477-A | Sulfonic ester derivatives, process for preparing the same, and use thereof | KANEKA CORPORATION (JP) | 2000-09-19 | — | — | US | disclosed |
| US-6093846-A | BY REACTING WITH SPECIFIED OPTICALLY ACTIVE AMINES SUCH AS CIS-1-AMINO-2-INDANOL IN A SOLVENT, PRODUCING TWO DIASTEREOISOMERIC SALTS OF DIFFERING SOLUBILITY, FRACTIONAL CRYSTALLIZATION AND DECOMPOSING THE SALT WITH ALKALI OR ACID | AJINOMOTO CO., INC. (JP) | 2000-07-25 | — | — | US | disclosed |
| US-6028217-A | CHEMICAL INTERMEDIATE FOR RENIN INHIBITOR OR ENKEPHALINASE ENZYME INHIBITOR | AJINOMOTO CO., INC. (JP) | 2000-02-22 | — | — | US | disclosed |
| US-6013829-A | REDUCING A MALONIC DIESTER, HYDRIDING TO OBTAIN A DIOL, ACETYLATING TO OBTAIN A MONOESTER, OXIDATION, SAPONIFICATION AND THIOACYLATING; ENZYME INHIBITORS; PROTEASES; OPTICS; ANTISECRETORY AND HYPOTENSIVE AGENTS | SOCIETE CIVILE BIOPROJET (FR) | 2000-01-11 | — | — | US | disclosed |
| EP-0916654-A1 | SULFONIC ESTER DERIVATIVES, PROCESS FOR PREPARING THE SAME, AND USE THEREOF | KANEKA CORPORATION (JP) | 1999-05-19 | — | — | EP | disclosed |
| EP-0906900-A1 | A process for preparing optically active 2-hydroxy-methyl-3-phenylpropionic acid | Ajinomoto Co., Inc. (JP) | 1999-04-07 | — | — | EP | disclosed |
| EP-0377139-B1 | N-substituted acylamino acid compounds, process for their production and their use | BANYU PHARMA CO LTD (JP) | 1995-07-12 | — | — | EP | disclosed |
| US-5424309-A | Hypotensive agents | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-06-13 | — | — | US | disclosed |
| EP-0377139-A1 | N-substituted acylamino acid compounds, process for their production and their use | Banyu Pharmaceutical Co., Ltd. (JP) | 1990-07-11 | — | — | EP | disclosed |
| EP-0353732-A2 | Fluoro-olefins, method for their preparation and their use | CIBA-GEIGY AG (CH) | 1990-02-07 | — | — | EP | disclosed |