Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20555410 | 0.87 | SMN1; SMN2 (0.40) | SMN1; SMN2POLBL3MBTL1ALDH1A1PKM | |
| SCHEMBL23152920 | 0.85 | SMN1; SMN2 (0.39) | SMN1; SMN2POLBL3MBTL1ALDH1A1PKM | |
| SCHEMBL16985268 | 0.83 | LRRK2 (0.41) | SMN1; SMN2POLBL3MBTL1ALDH1A1PKM | |
| SCHEMBL16975468 | 0.79 | SMN1; SMN2 (0.41) | SMN1; SMN2POLBL3MBTL1ALDH1A1PKM | |
| SCHEMBL15171010 | 0.78 | POLB (0.47) | SMN1; SMN2POLBL3MBTL1ALDH1A1PKM | |
| SCHEMBL16975306 | 0.78 | ALDH1A1 (0.41) | POLBALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL6154434 | 0.77 | SMN1; SMN2 (0.42) | SMN1; SMN2POLBL3MBTL1ALDH1A1PKM | |
| SCHEMBL16975314 | 0.77 | SMN1; SMN2 (0.39) | SMN1; SMN2POLBL3MBTL1ALDH1A1PKM | |
| SCHEMBL16985273 | 0.77 | ALDH1A1 (0.46) | SMN1; SMN2POLBL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL16975526 | 0.77 | SMN1; SMN2 (0.39) | SMN1; SMN2POLBL3MBTL1ALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101066950-A | 4-amino-5-methylpyrazole derivatives and process for producing the same | SANKYO AGRO CO LTD (JP) | 2007-11-07 | — | — | CN | disclosed |
| CN-101062918-A | 4-amino-5-methylpyrazole derivatives and process for producing the same | SANKYO AGRO CO LTD (JP) | 2007-10-31 | — | — | CN | disclosed |
| CN-101062917-A | 4-amino-5-methylpyrazole derivatives and process for producing the same | SANKYO AGRO CO LTD (JP) | 2007-10-31 | — | — | CN | disclosed |
| CN-1732155-A | 4-amino-5-methylpyrazole derivatives and process for producing the same | SANKYO AGRO CO LTD (JP) | 2006-02-08 | — | — | CN | disclosed |
| EP-1580189-A1 | 4-AMINO-5-METHYLPYRAZOLE DERIVATIVES AND PROCESS FOR PRODUCTION THEREOF | Sankyo Agro Company, Limited (JP) | 2005-09-28 | — | — | EP | disclosed |