Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CCKBR | P32239 | 1/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6154033 | 1.00 | SMN1; SMN2 (0.47) | SMN1; SMN2LMNAALDH1A1GAACYP1A2 | |
| SCHEMBL6154117 | 0.83 | LMNA (0.55) | SMN1; SMN2LMNAALDH1A1GAACYP1A2 | |
| SCHEMBL633303 | 0.83 | LMNA (0.55) | SMN1; SMN2LMNAALDH1A1GAACYP1A2 | |
| SCHEMBL633304 | 0.83 | LMNA (0.55) | SMN1; SMN2LMNAALDH1A1GAACYP1A2 | |
| SCHEMBL13897189 | 0.75 | CYP1A2 (0.50) | SMN1; SMN2LMNAALDH1A1GAACYP1A2 | |
| SCHEMBL20253696 | 0.75 | FABP7 (0.43) | SMN1; SMN2LMNAALDH1A1GAATSHR | |
| SCHEMBL31424314 | 0.74 | LMNA (0.50) | LMNAHTTTSHRL3MBTL1MAPT | |
| SCHEMBL2621408 | 0.74 | TMEM97 (0.49) | SMN1; SMN2LMNAALDH1A1GAACYP1A2 | |
| SCHEMBL30772550 | 0.74 | CYP1A2 (0.52) | SMN1; SMN2LMNAALDH1A1GAACYP1A2 | |
| SCHEMBL8393648 | 0.74 | LMNA (0.58) | SMN1; SMN2LMNAALDH1A1GAACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1553093-A1 | PROCESS FOR PREPARATION OF OPTICALLY ACTIVE 1-SUBSTITUTED AMINO-2,3-EPOXYPROPANES, INTERMEDIATES FOR THE SYNTHESIS THEREOF AND PROCESS FOR PREPARATION OF THE INTERMEDIATES | KANEKA CORPORATION (JP) | 2005-07-13 | — | — | EP | disclosed |