Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 4/20 | 0.30 |
| ▸ | CA1 | P00915 | 4/20 | 0.30 |
| ▸ | CA9 | Q16790 | 4/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6155239 | 0.72 | CNR1 (0.41) | HSP90AA1HSP90AB1CA12CA1CA9 | |
| SCHEMBL6156340 | 0.71 | CA12 (0.39) | HSP90AA1HSP90AB1CA12CA1CA9 | |
| SCHEMBL7706827 | 0.67 | CA1 (0.50) | HSP90AA1HSP90AB1CA12CA1CA9 | |
| SCHEMBL6155576 | 0.66 | CA12 (0.42) | HSP90AA1HSP90AB1CA12CA1CA9 | |
| SCHEMBL3093088 | 0.65 | HSP90AA1 (0.38) | HSP90AA1HSP90AB1CA12CA1CA9 | |
| SCHEMBL30628285 | 0.63 | CA12 (0.44) | HSP90AA1HSP90AB1CA12CA1CA9 | |
| SCHEMBL3571948 | 0.63 | CA12 (0.44) | HSP90AA1HSP90AB1CA12CA1CA9 | |
| SCHEMBL1077335 | 0.63 | CNR2 (0.42) | HSP90AA1HSP90AB1CA12CA1CA9 | |
| SCHEMBL3182564 | 0.63 | CA12 (0.46) | HSP90AA1HSP90AB1CA12CA1CA9 | |
| SCHEMBL6155570 | 0.62 | CYP4F2 (0.44) | HSP90AA1HSP90AB1CA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124779-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2005-02-02 | — | — | EP | disclosed |
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |