Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 4/20 | 0.41 |
| ▸ | CA1 | P00915 | 4/20 | 0.41 |
| ▸ | CA9 | Q16790 | 4/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | PREP | P48147 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6886658 | 0.85 | CNR1 (0.41) | HSP90AA1HSP90AB1CA12CA1CA9 | |
| SCHEMBL28433092 | 0.84 | HSP90AA1 (0.42) | HSP90AA1HSP90AB1CA12CA1CA9 | |
| SCHEMBL1077335 | 0.82 | CNR2 (0.42) | HSP90AA1HSP90AB1CA12CA1CA9 | |
| SCHEMBL10495504 | 0.81 | PREP (0.44) | CA12CA1CA9AKR1C3AKR1C2 | |
| SCHEMBL6155175 | 0.79 | HSP90AA1 (0.43) | HSP90AA1HSP90AB1CA12CA1CA9 | |
| SCHEMBL6155168 | 0.79 | HSP90AA1 (0.43) | HSP90AA1HSP90AB1CA12CA1CA9 | |
| SCHEMBL1356271 | 0.79 | AKR1C3 (0.52) | CYP4F2CYP4A11AKR1C3AKR1C2 | |
| SCHEMBL12585604 | 0.79 | CA12 (0.35) | CYP4F2CYP4A11HSP90AA1HSP90AB1CA12 | |
| SCHEMBL2989104 | 0.78 | AKR1C3 (0.53) | HSP90AA1HSP90AB1CA12CA1CA9 | |
| SCHEMBL7706827 | 0.78 | CA1 (0.50) | CYP4F2CYP4A11HSP90AA1HSP90AB1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124779-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2005-02-02 | — | — | EP | disclosed |
| EP-1235824-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2004-05-19 | — | — | EP | disclosed |
| EP-1235824-A1 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2002-09-04 | — | — | EP | disclosed |
| EP-1124779-A1 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2001-08-22 | — | — | EP | disclosed |
| WO-2001038320-A1 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2001-05-31 | — | — | WO | disclosed |
| WO-2000026167-A1 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2000-05-11 | — | — | WO | disclosed |
| EP-0486409-A1 | Method for protecting the products of multiplication of plants with the help of triazolyl/or imidazolyl-methyl allyl alcohols, and new compounds for this procedure | RHONE-POULENC AGROCHIMIE (FR) | 1992-05-20 | — | — | EP | disclosed |
| US-4876366-A | COENZYME REDUCTASE INHIBITORS | MERCK & CO., INC. (US) | 1989-10-24 | — | — | US | disclosed |
| EP-0245990-A2 | Antihypercholesterolemic compounds | MERCK & CO. INC. (US) | 1987-11-19 | — | — | EP | disclosed |