Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3371759 | 0.76 | PTPN1 (0.36) | — | |
| SCHEMBL14555987 | 0.75 | LMNA (0.42) | LMNAL3MBTL1PDE4ATDP1USP2 | |
| SCHEMBL7490863 | 0.73 | USP2 (0.41) | LMNAL3MBTL1PDE4ATDP1USP2 | |
| SCHEMBL10441292 | 0.73 | USP2 (0.41) | LMNAL3MBTL1PDE4ATDP1USP2 | |
| SCHEMBL16783046 | 0.71 | LMNA (0.34) | LMNAL3MBTL1PDE4ATDP1KDM4E | |
| SCHEMBL8377036 | 0.71 | LMNA (0.34) | LMNAL3MBTL1PDE4ATDP1KDM4E | |
| Phosphoric Acid SCHEMBL31621127 | 0.71 | PDE4A (0.45) | LMNAL3MBTL1PDE4ATDP1USP2 | |
| SCHEMBL4115003 | 0.71 | LMNA (0.48) | LMNAL3MBTL1PDE4ATDP1USP2 | |
| Phosphoric Acid SCHEMBL30931421 | 0.71 | PDE4A (0.45) | LMNAL3MBTL1PDE4ATDP1USP2 | |
| SCHEMBL18486467 | 0.70 | BTN3A1 (0.37) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1409548-A4 | LIGANDS TO ENHANCE CELLULAR UPTAKE OF BIOMOLECULES | CELL WORKS THERAPEUTICS INC (US) | 2005-08-31 | — | — | EP | claimed |
| EP-1409548-A2 | LIGANDS TO ENHANCE CELLULAR UPTAKE OF BIOMOLECULES | Cell Works Inc. (US) | 2004-04-21 | — | — | EP | claimed |
| WO-2003067209-A2 | LIGANDS TO ENHANCE CELLULAR UPTAKE OF BIOMOLECULES | CELL WORKS INC. (US) | 2003-08-14 | — | — | WO | claimed |