Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 20/20 | 0.71 |
| ▸ | ADRB1 | P08588 | 19/20 | 0.71 |
| ▸ | ADRB3 | P13945 | 19/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.71 |
| ▸ | HTR1A | P08908 | 2/20 | 0.71 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.71 |
| ▸ | HTR1B | P28222 | 2/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5281963 | 1.00 | ADRB2 (0.71) | ADRB2ADRB1ADRB3CYP3A4HTR1A | |
| Acetic Acid SCHEMBL5277610 | 0.96 | ADRB2 (0.73) | ADRB2ADRB1ADRB3CYP3A4HTR1A | |
| SCHEMBL5435474 | 0.92 | ADRB2 (0.80) | ADRB2ADRB1ADRB3CYP3A4HTR1A | |
| SCHEMBL5439728 | 0.90 | ADRB2 (0.79) | ADRB2ADRB1ADRB3CYP3A4HTR1A | |
| SCHEMBL5421704 | 0.90 | ADRB2 (0.78) | ADRB2ADRB1ADRB3CYP3A4HTR1A | |
| SCHEMBL5430018 | 0.89 | ADRB2 (0.85) | ADRB2ADRB1ADRB3CYP3A4HTR1A | |
| SCHEMBL5434019 | 0.89 | ADRB2 (0.83) | ADRB2ADRB1ADRB3CYP3A4HTR1A | |
| SCHEMBL5285805 | 0.89 | ADRB2 (0.71) | ADRB2ADRB1ADRB3CYP3A4HTR1A | |
| SCHEMBL5285799 | 0.89 | ADRB2 (0.71) | ADRB2ADRB1ADRB3CYP3A4HTR1A | |
| SCHEMBL5437108 | 0.89 | ADRB2 (0.58) | ADRB2ADRB1ADRB3CYP3A4HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1497261-A1 | PHENETHANOLAMINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2005-01-19 | — | — | EP | claimed |
| WO-2003091204-A1 | PHENETHANOLAMINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2003-11-06 | — | — | WO | claimed |