Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | BCL2 | P10415 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 11/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 11/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6156106 | 0.97 | APP (0.42) | APPBCL2MTNR1AMTNR1BBCHE | |
| SCHEMBL6155835 | 0.89 | APP (0.44) | APPBCL2MTNR1AMTNR1B | |
| SCHEMBL6156554 | 0.88 | BCL2 (0.43) | APPBCL2MTNR1AMTNR1B | |
| SCHEMBL6155493 | 0.86 | APP (0.44) | APPBCL2MTNR1AMTNR1B | |
| SCHEMBL6155868 | 0.86 | CETP (0.46) | BCL2MTNR1AMTNR1BBCHE | |
| SCHEMBL6157286 | 0.85 | BCL2 (0.41) | APPBCL2MTNR1AMTNR1B | |
| SCHEMBL6155129 | 0.82 | VDR (0.48) | APPBCL2MTNR1AMTNR1B | |
| SCHEMBL6156550 | 0.81 | BCL2 (0.41) | APPBCL2MTNR1AMTNR1B | |
| SCHEMBL2785504 | 0.80 | CYSLTR2 (0.40) | BCHE | |
| SCHEMBL6156102 | 0.80 | VDR (0.48) | APPMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124779-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2005-02-02 | — | — | EP | claimed |
| EP-1124779-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2005-02-02 | — | — | EP | disclosed |
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |
| EP-1124779-A1 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000026167-A1 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2000-05-11 | — | — | WO | disclosed |