Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.38 |
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6155361 | 1.00 | HTR2C (0.43) | HTR2CHTR2BGPR88KMT2AMEN1 | |
| SCHEMBL1586523 | 0.89 | MEN1 (0.52) | GPR88KMT2AMEN1MAPK1ALDH1A1 | |
| SCHEMBL1586594 | 0.78 | ALDH1A1 (0.41) | HTR2CHTR2BKMT2AMEN1MAPK1 | |
| SCHEMBL6130264 | 0.78 | ALDH1A1 (0.41) | HTR2CHTR2BKMT2AMEN1MAPK1 | |
| SCHEMBL16586861 | 0.73 | KDM1A (0.44) | KMT2AKDM1AHCRTR1HCRTR2 | |
| SCHEMBL16586862 | 0.73 | KDM1A (0.44) | KMT2AKDM1AHCRTR1HCRTR2 | |
| SCHEMBL16585271 | 0.73 | MEN1 (0.50) | KMT2AMEN1MAPK1ALDH1A1 | |
| SCHEMBL17985242 | 0.73 | MEN1 (0.50) | KMT2AMEN1MAPK1ALDH1A1 | |
| SCHEMBL30636963 | 0.73 | FFAR1 (0.47) | TTR | |
| SCHEMBL16585100 | 0.73 | MEN1 (0.50) | KMT2AMEN1MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1286955-B1 | ARYL AND HETEROARYLCYCLOPROPYL OXIME ETHERS AND THEIR USE AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2005-02-02 | — | — | EP | disclosed |
| EP-1286955-A1 | ARYL AND HETEROARYLCYCLOPROPYL OXIME ETHERS AND THEIR USE AS FUNGICIDES | Dow AgroSciences LLC (US) | 2003-03-05 | — | — | EP | disclosed |
| US-6348627-B1 | CONTROLLING PHYTOPATHOGENIC FUNGI | DOW AGROSCIENCES LLC | 2002-02-19 | — | — | US | disclosed |
| WO-2001087826-A1 | ARYL AND HETEROARYLCYCLOPROPYL OXIME ETHERS AND THEIR USE AS FUNGICIDES | ROHM AND HAAS COMPANY (US) | 2001-11-22 | — | — | WO | disclosed |