SCHEMBL6155414

SCHEMBL6155414

CC/C(=C\CC(O)C1CC1)c1cccc(CCc2ccc(CO)c(CO)c2)c1

nearest known ligand 0.52

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
VDR P11473 7/20 0.52
EPHX1 P07099 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6155422 1.00 VDR (0.52) VDREPHX1
SCHEMBL6155434 1.00 VDR (0.52) VDREPHX1
SCHEMBL6155201 0.85 VDR (0.58) VDR
SCHEMBL6155180 0.85 VDR (0.58) VDR
SCHEMBL6155192 0.85 VDR (0.58) VDR
SCHEMBL6155429 0.85 VDR (0.35) VDREPHX1
SCHEMBL6155500 0.74 VDR (0.59) VDR
SCHEMBL6155513 0.74 VDR (0.59) VDR
SCHEMBL6155505 0.74 VDR (0.59) VDR
SCHEMBL13406543 0.71 VDR (0.77) VDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1124779-B1 VITAMIN D ANALOGUES GALDERMA RES & DEV (FR) 2005-02-02 EP claimed
US-6689922-B1 BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) 2004-02-10 US claimed
EP-1124779-B1 VITAMIN D ANALOGUES GALDERMA RES & DEV (FR) 2005-02-02 EP disclosed
US-6689922-B1 BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) 2004-02-10 US disclosed