Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | RARA | P10276 | 1/20 | 0.32 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | RARG | P13631 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | RXRG | P48443 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 7/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.30 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.30 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6881366 | 1.00 | BACE1 (0.35) | BACE1RARARARBRARGRXRA | |
| SCHEMBL6881362 | 1.00 | BACE1 (0.35) | BACE1RARARARBRARGRXRA | |
| SCHEMBL6884293 | 0.84 | BACE1 (0.35) | BACE1RARARARBRARGRXRA | |
| SCHEMBL6155830 | 0.84 | BACE1 (0.35) | BACE1RARARARBRARGRXRA | |
| SCHEMBL6884295 | 0.84 | BACE1 (0.35) | BACE1RARARARBRARGRXRA | |
| SCHEMBL6155420 | 0.84 | ACACB (0.43) | BACE1ACACB | |
| SCHEMBL6155642 | 0.81 | MRGPRX4 (0.40) | — | |
| SCHEMBL6155645 | 0.81 | MRGPRX4 (0.40) | — | |
| SCHEMBL7777946 | 0.73 | FFAR1 (0.35) | BACE1FFAR1FFAR4 | |
| SCHEMBL6156525 | 0.73 | HSP90AA1 (0.41) | RARARARBRARGRXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124779-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2005-02-02 | — | — | EP | disclosed |
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |
| EP-1124779-A1 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000026167-A1 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2000-05-11 | — | — | WO | disclosed |