Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 7/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6881362 | 0.84 | BACE1 (0.35) | ACACBBACE1 | |
| SCHEMBL6881366 | 0.84 | BACE1 (0.35) | ACACBBACE1 | |
| SCHEMBL6155470 | 0.84 | BACE1 (0.35) | ACACBBACE1 | |
| SCHEMBL6156231 | 0.81 | MAOB (0.41) | BACE1MAOB | |
| SCHEMBL7777946 | 0.79 | FFAR1 (0.35) | BACE1 | |
| SCHEMBL22432227 | 0.77 | PKM (0.40) | BACE1HPGD | |
| SCHEMBL6155252 | 0.77 | MAOB (0.52) | MAOBRAB9A | |
| SCHEMBL6885569 | 0.77 | FFAR1 (0.46) | — | |
| SCHEMBL6155990 | 0.76 | PPARA (0.42) | BACE1MAOBHPGDLMNARAB9A | |
| SCHEMBL6878730 | 0.75 | FFAR1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124779-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2005-02-02 | — | — | EP | disclosed |
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |
| EP-1124779-A1 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000026167-A1 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2000-05-11 | — | — | WO | disclosed |