Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 4/20 | 0.68 |
| ▸ | MAOB | P27338 | 13/20 | 0.43 |
| ▸ | MAOA | P21397 | 4/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6155488 | 1.00 | VDR (0.68) | VDRMAOBMAOANR4A1NR4A2 | |
| SCHEMBL6155491 | 1.00 | VDR (0.68) | VDRMAOBMAOANR4A1NR4A2 | |
| SCHEMBL2801798 | 0.92 | VDR (0.80) | VDRMAOBMAOANR4A1NR4A2 | |
| SCHEMBL2801805 | 0.92 | VDR (0.80) | VDRMAOBMAOANR4A1NR4A2 | |
| SCHEMBL2801791 | 0.92 | VDR (0.80) | VDRMAOBMAOANR4A1NR4A2 | |
| SCHEMBL2107507 | 0.91 | VDR (0.66) | VDRMAOBMAOANR4A1NR4A2 | |
| SCHEMBL2107505 | 0.91 | VDR (0.66) | VDRMAOBMAOANR4A1NR4A2 | |
| SCHEMBL2781752 | 0.84 | VDR (0.67) | VDRMAOBF2 | |
| SCHEMBL2781760 | 0.84 | VDR (0.67) | VDRMAOBF2 | |
| SCHEMBL2781748 | 0.84 | VDR (0.67) | VDRMAOBF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124779-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2005-02-02 | — | — | EP | disclosed |
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |