Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 10/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 9/20 | 0.47 |
| ▸ | MME | P08473 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8446169 | 1.00 | KMT2A (0.47) | KMT2APPARGEPHX2PPARAMME | |
| SCHEMBL6154118 | 0.86 | CYP1A2 (0.59) | MMECYP1A2 | |
| SCHEMBL6154367 | 0.86 | CYP1A2 (0.59) | MMECYP1A2 | |
| SCHEMBL6427020 | 0.86 | CYP1A2 (0.59) | MMECYP1A2 | |
| SCHEMBL4663230 | 0.79 | CYP1A2 (0.65) | KMT2APPARGEPHX2PPARACYP1A2 | |
| SCHEMBL6154294 | 0.78 | MME (0.41) | KMT2APPARGPPARAMMEMEN1 | |
| SCHEMBL22800347 | 0.77 | KMT2A (0.50) | KMT2APPARGEPHX2PPARACYP1A2 | |
| SCHEMBL22800348 | 0.77 | KMT2A (0.50) | KMT2APPARGEPHX2PPARACYP1A2 | |
| SCHEMBL6153821 | 0.76 | MME (0.39) | KMT2APPARGEPHX2PPARAMME | |
| SCHEMBL7713441 | 0.76 | PPARG (0.71) | KMT2APPARGEPHX2PPARACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0916654-B1 | SULFONIC ESTER DERIVATIVES, PROCESS FOR PREPARING THE SAME, AND USE THEREOF | KANEKA CORP (JP) | 2005-02-23 | — | — | EP | disclosed |
| US-6410773-B1 | OPTICAL ACTIVE MATERIAL; ENKEPHALINASE INHIBITORS; HYPOTENSIVE AGENTS | KANEKA CORPORATION (JP) | 2002-06-25 | — | — | US | disclosed |
| US-6121477-A | Sulfonic ester derivatives, process for preparing the same, and use thereof | KANEKA CORPORATION (JP) | 2000-09-19 | — | — | US | disclosed |