Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 2/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1361328 | 0.85 | FFAR3 (0.38) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL6156183 | 0.75 | HDAC3 (0.43) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL1361296 | 0.75 | HDAC3 (0.43) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL1362531 | 0.73 | HDAC3 (0.44) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL6155554 | 0.73 | — | — | |
| SCHEMBL1361270 | 0.72 | FFAR3 (0.40) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL1361325 | 0.72 | FFAR3 (0.40) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL1359966 | 0.72 | CA1 (0.41) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL50797 | 0.72 | FFAR3 (0.40) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL10904203 | 0.72 | CA2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1252214-B1 | ORGANOMETALLIC COMPOSITIONS | JOHNSON MATTHEY PLC (GB) | 2005-11-09 | — | — | EP | disclosed |
| US-6762314-B2 | FOR USE AS CURING AGENT IN COATINGS, COMPOSITE MATERIALS, ADHESIVES, FOAMS AND THERMOPLASTIC POLYURETHANES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 2004-07-13 | — | — | US | disclosed |
| US-20030009043-A1 | Organometallic compositions | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 2003-01-09 | — | — | US | disclosed |
| EP-1252214-A1 | ORGANOMETALLIC COMPOSITIONS | Imperial Chemical Industries PLC (GB) | 2002-10-30 | — | — | EP | disclosed |
| WO-2001051536-A1 | ORGANOMETALLIC COMPOSITIONS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 2001-07-19 | — | — | WO | disclosed |