Sugi Predict

Sugi Predict / Compounds / Trifluoroacetic Acid

Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL6155593

NC(=O)CCc1ccccc1.O=C(O)C(F)(F)F

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KEAP1 Q14145 1/20 0.59
▸ FFAR1 O14842 3/20 0.55
▸ CES1 P23141 5/20 0.53
▸ FAAH O00519 3/20 0.53
▸ PRMT1 Q99873 1/20 0.51
▸ ALDH1A1 P00352 1/20 0.50
▸ TSHR P16473 1/20 0.47
▸ HDAC2 Q92769 2/20 0.47
▸ HDAC8 Q9BY41 2/20 0.47
▸ HDAC6 Q9UBN7 2/20 0.47
▸ TDP1 Q9NUW8 1/20 0.47
▸ POLB P06746 1/20 0.46
▸ GAA P10253 1/20 0.46
▸ HDAC1 Q13547 2/20 0.46
▸ HDAC3 O15379 1/20 0.46
▸ MAPK1 P28482 1/20 0.46
▸ ADRA1A P35348 1/20 0.46
▸ HDAC4 P56524 1/20 0.46
▸ SLC6A3 Q01959 1/20 0.46
▸ SMN1; SMN2 Q16637 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL30882532 0.91 CES1 (0.60) KEAP1FFAR1CES1FAAHHDAC2
Trifluoroacetic Acid SCHEMBL30483155 0.91 CES1 (0.60) KEAP1FFAR1CES1FAAHHDAC2
SCHEMBL2593 0.88 KEAP1 (0.67) KEAP1FFAR1PRMT1ALDH1A1HDAC2
Phenyl Propionic Acid SCHEMBL27428011 0.86 KEAP1 (0.79) KEAP1FFAR1CES1FAAHALDH1A1
Ammonia Solution, Strong SCHEMBL10416110 0.86 KEAP1 (0.64) KEAP1FFAR1PRMT1ALDH1A1HDAC2
Hydrochloric Acid SCHEMBL6952080 0.86 KEAP1 (0.64) KEAP1FFAR1PRMT1ALDH1A1HDAC2
Bicarbonate SCHEMBL28311766 0.86 KEAP1 (0.64) KEAP1FFAR1PRMT1ALDH1A1HDAC2
Hydrochloric Acid SCHEMBL3308277 0.86 KEAP1 (0.64) KEAP1FFAR1PRMT1ALDH1A1HDAC2
Hydrazine SCHEMBL28262207 0.86 KEAP1 (0.64) KEAP1FFAR1PRMT1ALDH1A1HDAC2
Fluoride SCHEMBL27900680 0.86 KEAP1 (0.64) KEAP1FFAR1PRMT1ALDH1A1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101962365-A Aminoindazole derivatives as protein-kinase inhibitors AVENTIS PHARMA SA 2011-02-02 — — CN claimed
CN-1656078-A Aminoindazole derivatives as protein kinase inhibitors AVENTIS PHARMA SA (FR) 2005-08-17 — — CN claimed
CN-114521199-B Cross-linked alginic acid structure 持田制药株式会社 2025-05-30 — — CN disclosed
CN-106967151-A The endomorphins of many Sites Combination modifications are like thing and its synthesis and application 兰州大学 2017-07-21 — — CN disclosed
CN-101962365-A Aminoindazole derivatives as protein-kinase inhibitors AVENTIS PHARMA SA 2011-02-02 — — CN disclosed
CN-1656078-A Aminoindazole derivatives as protein kinase inhibitors AVENTIS PHARMA SA (FR) 2005-08-17 — — CN disclosed
EP-1511764-A2 PEPTIDES AND PEPTIDOMIMETICS USEFUL FOR INHIBITING THE ACTIVITY OF PROSTAGLANDIN F sb 2a /sb RECEPTOR THERATECHNOLOGIES INC. (CA) 2005-03-09 — — EP disclosed
US-6759420-B1 LOW MOLECULAR WEIGHT, FACTOR XA SPECIFIC BLOOD CLOTTING INHIBITORS WITHOUT SIDE EFFECTS AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2004-07-06 — — US disclosed
WO-2003104266-A2 PEPTIDES AND PEPTIDOMIMETICS USEFUL FOR INHIBITING THE ACTIVITY OF PROSTAGLANDIN F2α RECEPTOR THERATECHNOLOGIES INC. (CA) 2003-12-18 — — WO disclosed
US-6245746-B1 ADMINISTERING AMIDE MICROBIOCIDE ANTIBIOTIC MICROCIDE PHARMACEUTICALS, INC. 2001-06-12 — — US disclosed
US-6114310-A THERAPY FOR MICROBIAL INFECTIONS MICROCIDE PHARMACEUTICALS, INC. (US) 2000-09-05 — — US disclosed
WO-1999037667-A1 EFFLUX PUMP INHIBITORS MICROCIDE PHARMACEUTICALS, INC. (US) 1999-07-29 — — WO disclosed