Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 12/20 | 0.43 |
| ▸ | CA12 | O43570 | 5/20 | 0.42 |
| ▸ | CA9 | Q16790 | 5/20 | 0.42 |
| ▸ | CA1 | P00915 | 10/20 | 0.41 |
| ▸ | GRIA4 | P48058 | 4/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5186014 | 1.00 | KIF11 (0.51) | KIF11CA2CA12CA9CA1 | |
| SCHEMBL6155981 | 1.00 | KIF11 (0.51) | KIF11CA2CA12CA9CA1 | |
| SCHEMBL3711628 | 0.90 | GRIA4 (0.48) | KIF11CA2CA1GRIA4 | |
| SCHEMBL13255710 | 0.90 | GRIA4 (0.48) | KIF11CA2CA1GRIA4 | |
| SCHEMBL13663202 | 0.86 | GRIA4 (0.43) | KIF11CA2CA1GRIA4 | |
| SCHEMBL6561639 | 0.86 | GRIA4 (0.51) | CA2CA12CA9CA1GRIA4 | |
| SCHEMBL5186189 | 0.85 | GRIA4 (0.54) | KIF11GRIA4 | |
| SCHEMBL5187868 | 0.84 | CYP2C19 (0.45) | KIF11CA2CA12CA9CA1 | |
| SCHEMBL5186190 | 0.82 | GRIA4 (0.44) | CA2CA12CA9CA1GRIA4 | |
| SCHEMBL5186129 | 0.82 | GRIA4 (0.41) | KIF11GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1330233-B1 | METHOD OF TREATING STROKE | LILLY CO ELI (US) | 2005-02-02 | — | — | EP | disclosed |
| US-20040063680-A1 | Method of treating stroke | CLEMENS JAMES ALLEN (US) | 2004-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063680-A1 | Method of treating stroke | ASAH2, PCSK7, PCSK9 | KIF11 338/4885CA2 233/4885CA12 422/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.