Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6156166 | 0.83 | ALDH1A1 (0.33) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL6155659 | 0.82 | EPHX2 (0.33) | MAPTMEN1MAPK1KMT2A | |
| SCHEMBL6154015 | 0.74 | MAPT (0.36) | MAPTMEN1MAPK1KMT2AKDM4E | |
| SCHEMBL8428364 | 0.74 | MEN1 (0.40) | MAPTMEN1MAPK1KMT2A | |
| SCHEMBL6155078 | 0.73 | MEN1 (0.35) | MAPTMEN1MAPK1KMT2AKDM4E | |
| SCHEMBL4982952 | 0.70 | HSD17B10 (0.45) | MAPTMAPK1KDM4EALDH1A1HPGD | |
| SCHEMBL6155378 | 0.70 | ALDH1A1 (0.35) | MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL6156390 | 0.70 | MEN1 (0.35) | MAPTMEN1MAPK1KMT2AKDM4E | |
| Bromide SCHEMBL6154601 | 0.69 | ALDH1A1 (0.34) | MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL6155352 | 0.68 | EPHX2 (0.37) | MAPTKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1517882-A1 | AMIDE LINKER PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-03-30 | — | — | EP | disclosed |
| WO-2004000789-A1 | AMIDE LINKER PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2003-12-31 | — | — | WO | disclosed |
| EP-0918460-A1 | METHODS OF TREATMENT OF EYE TRAUMA AND DISORDERS | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1999-06-02 | — | — | EP | disclosed |
| WO-1999002145-A1 | COMBINATION DRUG THERAPIES COMPRISING AMINOGLYCOSIDE ANTIBIOTICS AND N,N'-DISUBSTITUTED GUANIDINES | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1999-01-21 | — | — | WO | disclosed |
| WO-1998004131-A1 | METHODS OF TREATMENT OF EYE TRAUMA AND DISORDERS | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1998-02-05 | — | — | WO | disclosed |