Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 9/20 | 0.64 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.30 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6156222 | 1.00 | VDR (0.64) | VDRCYP4F2CYP4A11 | |
| SCHEMBL6156215 | 1.00 | VDR (0.64) | VDRCYP4F2CYP4A11 | |
| SCHEMBL6155550 | 0.84 | VDR (0.74) | VDR | |
| SCHEMBL6155555 | 0.84 | VDR (0.74) | VDR | |
| SCHEMBL6155561 | 0.84 | VDR (0.74) | VDR | |
| SCHEMBL6156219 | 0.82 | VDR (0.44) | VDR | |
| SCHEMBL3280246 | 0.82 | VDR (0.77) | VDRCYP4F2CYP4A11 | |
| SCHEMBL3280253 | 0.82 | VDR (0.77) | VDRCYP4F2CYP4A11 | |
| SCHEMBL3280240 | 0.82 | VDR (0.77) | VDRCYP4F2CYP4A11 | |
| SCHEMBL3280656 | 0.78 | VDR (1.00) | VDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124779-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2005-02-02 | — | — | EP | claimed |
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | claimed |
| EP-1124779-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2005-02-02 | — | — | EP | disclosed |
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |