Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 4/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 10/20 | 0.37 |
| ▸ | VDR | P11473 | 2/20 | 0.36 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.34 |
| ▸ | RELA | Q04206 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6154757 | 0.93 | VDR (0.44) | F2MRGPRX4VDRTP53PKM | |
| SCHEMBL6155760 | 0.93 | VDR (0.42) | F2VDRMAOB | |
| SCHEMBL6155650 | 0.87 | MRGPRX4 (0.42) | MRGPRX4TP53PKMNFKB1NFKB2 | |
| SCHEMBL6158586 | 0.86 | VDR (0.35) | VDR | |
| SCHEMBL6155257 | 0.82 | MAOB (0.52) | MRGPRX4TP53PKMNFKB1NFKB2 | |
| SCHEMBL6155584 | 0.79 | VDR (0.36) | VDR | |
| SCHEMBL6155841 | 0.78 | VDR (0.55) | F2MRGPRX4VDRF10TP53 | |
| SCHEMBL6155837 | 0.78 | VDR (0.55) | F2MRGPRX4VDRF10TP53 | |
| SCHEMBL6155848 | 0.78 | VDR (0.55) | F2MRGPRX4VDRF10TP53 | |
| SCHEMBL6155843 | 0.77 | MRGPRX4 (0.46) | F2MRGPRX4F10TP53PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124779-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2005-02-02 | — | — | EP | disclosed |