SCHEMBL6156329

SCHEMBL6156329

CC/C(=C/C=C/C(O)(CC)CC)c1cc(OCc2ccc(CO)c(CO)c2)ccc1C

nearest known ligand 0.71

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
VDR P11473 5/20 0.71
MAOB P27338 3/20 0.33
MAOA P21397 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6156326 1.00 VDR (0.71) VDRMAOBMAOA
SCHEMBL6156335 1.00 VDR (0.71) VDRMAOBMAOA
SCHEMBL6155221 0.88 VDR (0.68) VDR
SCHEMBL6155232 0.88 VDR (0.68) VDR
SCHEMBL6155223 0.88 VDR (0.68) VDR
SCHEMBL6156334 0.83 VDR (0.48) VDRMAOBMAOA
SCHEMBL2781792 0.83 VDR (1.00) VDRMAOBMAOA
SCHEMBL2783741 0.83 VDR (1.00) VDRMAOBMAOA
SCHEMBL2781782 0.83 VDR (1.00) VDRMAOBMAOA
SCHEMBL2781784 0.83 VDR (1.00) VDRMAOBMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1124779-B1 VITAMIN D ANALOGUES GALDERMA RES & DEV (FR) 2005-02-02 EP claimed
US-6689922-B1 BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) 2004-02-10 US claimed
EP-1124779-B1 VITAMIN D ANALOGUES GALDERMA RES & DEV (FR) 2005-02-02 EP disclosed
US-6689922-B1 BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) 2004-02-10 US disclosed
EP-1124779-A1 VITAMIN D ANALOGUES Galderma Research & Development, S.N.C. (FR) 2001-08-22 EP disclosed
WO-2000026167-A1 VITAMIN D ANALOGUES GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) 2000-05-11 WO disclosed