Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | C1S | P09871 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | OGG1 | O15527 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6156405 | 1.00 | PTGS1 (0.34) | PTGS1PTGS2C1SPARP1KDM4E | |
| SCHEMBL6156076 | 0.86 | PRSS1 (0.36) | PTGS1PTGS2 | |
| SCHEMBL6156073 | 0.86 | PRSS1 (0.36) | PTGS1PTGS2 | |
| SCHEMBL6156078 | 0.86 | PRSS1 (0.36) | PTGS1PTGS2 | |
| SCHEMBL7050636 | 0.85 | PTGS1 (0.32) | PTGS1PTGS2 | |
| SCHEMBL7050628 | 0.85 | PTGS1 (0.32) | PTGS1PTGS2 | |
| SCHEMBL7050634 | 0.85 | PTGS1 (0.32) | PTGS1PTGS2 | |
| SCHEMBL6564835 | 0.83 | CYP1A2 (0.34) | KDM4EPOLBGAAMAPTL3MBTL1 | |
| SCHEMBL6564825 | 0.83 | CYP1A2 (0.34) | KDM4EPOLBGAAMAPTL3MBTL1 | |
| SCHEMBL6564833 | 0.83 | CYP1A2 (0.34) | KDM4EPOLBGAAMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124779-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2005-02-02 | — | — | EP | disclosed |
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |