Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | VDR | P11473 | 2/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6156076 | 1.00 | PRSS1 (0.36) | PRSS1PRSS2PRSS3VDRPTGS1 | |
| SCHEMBL6156073 | 1.00 | PRSS1 (0.36) | PRSS1PRSS2PRSS3VDRPTGS1 | |
| SCHEMBL6156808 | 0.87 | PRSS1 (0.37) | PRSS1PRSS2PRSS3PTGS1PTGS2 | |
| SCHEMBL6156807 | 0.87 | PRSS1 (0.37) | PRSS1PRSS2PRSS3PTGS1PTGS2 | |
| SCHEMBL6156405 | 0.86 | PTGS1 (0.34) | PTGS1PTGS2 | |
| SCHEMBL6156409 | 0.86 | PTGS1 (0.34) | PTGS1PTGS2 | |
| SCHEMBL6566186 | 0.84 | — | — | |
| SCHEMBL6566192 | 0.84 | — | — | |
| SCHEMBL7050636 | 0.83 | PTGS1 (0.32) | PTGS1PTGS2 | |
| SCHEMBL7050628 | 0.83 | PTGS1 (0.32) | PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124779-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2005-02-02 | — | — | EP | disclosed |
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |
| EP-1124779-A1 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000026167-A1 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2000-05-11 | — | — | WO | disclosed |