⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2123312 | 0.81 | ALDH1A1 (0.44) | — | |
| SCHEMBL9259450 | 0.80 | — | — | |
| SCHEMBL17695708 | 0.80 | — | — | |
| SCHEMBL776386 | 0.80 | ALDH1A1 (0.33) | — | |
| SCHEMBL16939030 | 0.78 | — | — | |
| SCHEMBL2123956 | 0.78 | PTPN7 (0.40) | — | |
| SCHEMBL16885822 | 0.75 | ALDH1A1 (0.39) | — | |
| SCHEMBL2939625 | 0.74 | — | — | |
| SCHEMBL18832502 | 0.74 | — | — | |
| SCHEMBL16408712 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024010782-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING WRN HELICASE INHIBITORS | VIVIDION THERAPEUTICS, INC. (US) | 2024-01-11 | — | — | WO | disclosed |
| WO-2017156495-A1 | COMPOUNDS AND METHODS FOR MODULATING BRUTON'S TYROSINE KINASE | CORVUS PHARMACEUTICALS, INC. (US) | 2017-09-14 | — | — | WO | disclosed |
| US-20150247034-A1 | THERMOSETTING LIQUID-CRYSTAL POLYESTER COMPOSITION AND CURED PRODUCT THEREOF | POLYPLASTICS CO., LTD. (JP) | 2015-09-03 | — | — | US | disclosed |
| US-8362261-B2 | Process for preparing pyridyl-substituted pyrazoles | BAYER CROPSCIENCE AG (DE) | 2013-01-29 | — | — | US | disclosed |
| US-7825237-B2 | Oligonucleotides and analogs labeled with energy transfer dyes | APPLIED BIOSYSTEMS, LLC (US) | 2010-11-02 | — | — | US | disclosed |
| US-20100029923-A1 | OLIGONUCLEOTIDES AND ANALOGS LABELED WITH ENERGY TRANSFER DYES | Life Technologies Corporation (US) | 2010-02-04 | — | — | US | disclosed |
| US-7452672-B2 | Methods of analyzing polynucleotides employing energy transfer dyes | APPLIED BIOSYSTEMS INC. (US) | 2008-11-18 | — | — | US | disclosed |
| US-7388092-B2 | Oligonucleotides and analogs labeled with energy transfer dyes | APPLERA CORPORATION (US) | 2008-06-17 | — | — | US | disclosed |
| US-20080027059-A1 | SUBSTITUTED ISOXAZOLINES, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME, METHODS OF PREPARING SAME, AND USES OF SAME | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-01-31 | — | — | US | disclosed |
| US-20070161027-A1 | OLIGONUCLEOTIDES AND ANALOGS LABELED WITH ENERGY TRANSFER DYES | APPLERA CORPORATION (US) | 2007-07-12 | — | — | US | disclosed |
| US-20070154927-A1 | ENERGY TRANSFER DYES WITH ENHANCED FLUORESCENCE | APPLERA CORPORATION (US) | 2007-07-05 | — | — | US | disclosed |
| US-20070154926-A1 | Linkers for donor dyes to acceptor dyes for energy transfer between dyes with fluorescence | APPLERA CORPORATION (US) | 2007-07-05 | — | — | US | disclosed |
| EP-1212285-B1 | METHOD OF PRODUCING 2-HYDROXYCARBOXYLIC ACID ESTERS | ABBOTT GMBH & CO KG (DE) | 2005-02-02 | — | — | EP | disclosed |
| US-6646152-B1 | Decyclization of glycidyl ester using organoaluminum reagent; no side reactions | ABBOTT GMBH & CO. KG (DE) | 2003-11-11 | — | — | US | disclosed |